SCHEMBL23628245

SCHEMBL23628245

OC1(c2cccc(Cl)c2-c2ccccc2)C2CC3CC(C2)CC1C3

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 6/20 0.40
PDK2 Q15119 3/20 0.40
FABP3 P05413 4/20 0.35
FABP4 P15090 4/20 0.35
FABP5 Q01469 1/20 0.35
AKR1B1 P15121 1/20 0.33
P2RX7 Q99572 1/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
HTT P42858 1/20 0.32
AKT1 P31749 1/20 0.31
AKT2 P31751 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25501422 0.90 HSD11B1 (0.37) HSD11B1PDK2P2RX7
SCHEMBL24618124 0.85 PDK2 (0.50) HSD11B1PDK2P2RX7HTT
SCHEMBL24626840 0.81 PDK2 (0.37) PDK2FABP3FABP4FABP5P2RX7
SCHEMBL24316401 0.79 AKR1B1 (0.40) HSD11B1PDK2FABP4FABP5AKR1B1
SCHEMBL25501503 0.79 PDK2 (0.39) HSD11B1PDK2
SCHEMBL25818524 0.78 AHR (0.38) HSD11B1PDK2HTT
SCHEMBL25818545 0.78 ALDH1A1 (0.33) HSD11B1PDK2
SCHEMBL22797180 0.78 CYP2A6 (0.43) HSD11B1PDK2P2RX7
SCHEMBL25054783 0.77 PDK2 (0.44) HSD11B1PDK2P2RX7HTT
SCHEMBL23319128 0.77 PDK2 (0.44) HSD11B1PDK2P2RX7HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
WO-2021135456-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM HSD11B1 3861/4885PDK2 639/4885FABP3 3811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.