Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GRN | P28799 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2355532 | 0.90 | ALDH1A1 (0.41) | ALDH1A1KDM4EGRNSORT1PKM | |
| SCHEMBL15941810 | 0.83 | ALDH1A1 (0.52) | ALDH1A1KDM4EGRNSORT1PKM | |
| SCHEMBL2362846 | 0.78 | GRN (0.61) | ALDH1A1KDM4EGRNSORT1PKM | |
| SCHEMBL2364403 | 0.75 | ALDH1A1 (0.38) | ALDH1A1KDM4EGRNSORT1PKM | |
| SCHEMBL3416368 | 0.70 | SMN1; SMN2 (0.43) | KDM4EGRNSORT1KMT2A | |
| SCHEMBL18241096 | 0.69 | PKM (0.51) | ALDH1A1PKMKMT2ANPC1L3MBTL1 | |
| SCHEMBL2362819 | 0.69 | KDM4E (0.35) | KDM4EPKMKMT2ANPC1 | |
| SCHEMBL10959178 | 0.68 | ALDH1A1 (0.39) | ALDH1A1KDM4EGRNSORT1PKM | |
| SCHEMBL2355530 | 0.66 | GRN (0.67) | ALDH1A1KDM4EGRNSORT1PKM | |
| SCHEMBL2362715 | 0.66 | PKM (0.35) | KDM4EPKMNPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352723-B1 | PESTICIDAL N-ARYL- OR N-HETEROARYL PYRAZOLE CARBOXAMIDE COMPOUNDS | BAYER IP GMBH (DE) | 2016-11-23 | — | — | EP | disclosed |
| EP-2352723-A2 | HALOGEN-SUBSTITUTED COMPOUNDS USED AS PESTICIDES | Bayer CropScience AG (DE) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010051926-A2 | NEW HALOGEN-SUBSTITUTED BONDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-05-14 | — | — | WO | disclosed |
| EP-2184273-A1 | Halogen substituted compounds as pesticides | Bayer CropScience AG (DE) | 2010-05-12 | — | — | EP | disclosed |