SCHEMBL23629353

SCHEMBL23629353

CCSc1cc(Br)cnc1C(=O)CC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
ALDH1A1 P00352 4/20 0.34
PKM P14618 1/20 0.34
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
NPY1R P25929 1/20 0.32
NPY2R P49146 1/20 0.32
KDM4E B2RXH2 1/20 0.32
POLB P06746 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
HTT P42858 2/20 0.31
GAA P10253 2/20 0.31
RAB9A P51151 2/20 0.31
RECQL P46063 1/20 0.31
HPGD P15428 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
AOC3 Q16853 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21586206 0.89 MAPT (0.37) MAPTSMN1; SMN2ALDH1A1PKMKMT2A
SCHEMBL17422370 0.86 POLB (0.40) MAPTSMN1; SMN2ALDH1A1PKMKMT2A
SCHEMBL30107041 0.86 SMN1; SMN2 (0.39) MAPTSMN1; SMN2ALDH1A1PKMKMT2A
SCHEMBL17732146 0.86 SMN1; SMN2 (0.39) MAPTSMN1; SMN2ALDH1A1PKMKMT2A
Hydrochloric Acid SCHEMBL28618285 0.84 POLB (0.39) MAPTSMN1; SMN2ALDH1A1PKMKMT2A
SCHEMBL30989780 0.84 SMN1; SMN2 (0.38) MAPTSMN1; SMN2ALDH1A1PKMKMT2A
SCHEMBL25887585 0.84 SMN1; SMN2 (0.38) MAPTSMN1; SMN2ALDH1A1PKMKMT2A
SCHEMBL17422436 0.84 MAPT (0.38) MAPTSMN1; SMN2ALDH1A1PKMKMT2A
SCHEMBL30969148 0.82 HPGD (0.42) MAPTSMN1; SMN2ALDH1A1KMT2AMEN1
SCHEMBL25210087 0.82 HPGD (0.42) MAPTSMN1; SMN2ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848362-B1 HETEROARYL AZOLE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO (JP) 2025-10-29 EP disclosed
US-12180178-B2 Heteroaryl azole compound and pest control agent NIPPON SODA CO., LTD. (JP) 2024-12-31 US disclosed
EP-4455135-A2 HETEROARYL AZOLE COMPOUND AND PEST CONTROL AGENT Nippon Soda Co., Ltd. (JP) 2024-10-30 EP disclosed
US-20240327377-A1 HETEROARYL AZOLE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2024-10-03 US disclosed
EP-3848362-A1 HETEROARYL AZOLE COMPOUND AND PEST CONTROL AGENT Nippon Soda Co., Ltd. (JP) 2021-07-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240327377-A1 HETEROARYL AZOLE COMPOUND AND PEST CONTROL AGENT INF2, CRY2, CRY1 MAPT 379/4885SMN1; SMN2 1194/4885ALDH1A1 4254/4885
US-12180178-B2 Heteroaryl azole compound and pest control agent CRY1, CRY2, H1-2 MAPT 329/4885SMN1; SMN2 2590/4885ALDH1A1 4574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.