SCHEMBL30107041

SCHEMBL30107041

CCSc1cc(Br)cnc1C(C)=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.39
MAPT P10636 3/20 0.39
ALDH1A1 P00352 3/20 0.35
PKM P14618 1/20 0.35
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
NPY1R P25929 1/20 0.32
NPY2R P49146 1/20 0.32
GAA P10253 2/20 0.32
HTT P42858 2/20 0.32
DYRK1A Q13627 2/20 0.32
HPGD P15428 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
AOC3 Q16853 1/20 0.31
DYRK1B Q9Y463 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17732146 1.00 SMN1; SMN2 (0.39) SMN1; SMN2MAPTALDH1A1PKMKDM4E
SCHEMBL17422370 0.87 POLB (0.40) SMN1; SMN2MAPTALDH1A1PKMKDM4E
SCHEMBL17422436 0.86 MAPT (0.38) SMN1; SMN2MAPTALDH1A1PKMKDM4E
Hydrochloric Acid SCHEMBL28618285 0.86 POLB (0.39) SMN1; SMN2MAPTALDH1A1PKMKDM4E
SCHEMBL25887585 0.86 SMN1; SMN2 (0.38) SMN1; SMN2MAPTALDH1A1PKMKDM4E
SCHEMBL23629353 0.86 MAPT (0.38) SMN1; SMN2MAPTALDH1A1PKMKDM4E
SCHEMBL30989780 0.86 SMN1; SMN2 (0.38) SMN1; SMN2MAPTALDH1A1PKMKDM4E
SCHEMBL21586206 0.84 MAPT (0.37) SMN1; SMN2MAPTALDH1A1PKMKDM4E
SCHEMBL17422583 0.83 MAPT (0.41) SMN1; SMN2MAPTALDH1A1PKMKDM4E
SCHEMBL29657379 0.83 SMN1; SMN2 (0.41) SMN1; SMN2MAPTALDH1A1PKMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025229111-A1 PYRIMIDINONE DERIVATIVES AS PESTICIDAL COMPOUNDS BASF SE (DE) 2025-11-06 WO disclosed
EP-4634188-A1 PYRIMIDINONE DERIVATIVES AS PESTICIDAL COMPOUNDS BASF SE (DE) 2025-10-22 EP disclosed
CN-119431377-A Pesticidally active heterocyclic derivatives with sulfoximine containing substituents 先正达农作物保护股份公司 2025-02-14 CN disclosed
US-20250026757-A1 Bicyclic Compounds for the Control of Invertebrate Pests BASF SE (DE) 2025-01-23 US disclosed
EP-4433479-A1 BICYCLIC COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS BASF SE (DE) 2024-09-25 EP disclosed
CN-118355017-A Bicyclic compounds for controlling invertebrate pests 巴斯夫欧洲公司 2024-07-16 CN disclosed
CN-118355004-A Cyclopropyl- (heteroaryl) -substituted ethylsulfonyl-pyridine derivatives 勃林格殷格翰动物保健有限公司 2024-07-16 CN disclosed
WO-2024126117-A1 PYRIMIDINONE DERIVATIVES AS PESTICIDAL COMPOUNDS BASF SE (DE) 2024-06-20 WO disclosed
CN-116600645-A Sulfinimide pesticide 巴斯夫欧洲公司 2023-08-15 CN disclosed
WO-2023088718-A1 BICYCLIC COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS BASF SE (DE) 2023-05-25 WO disclosed
CN-110612301-B Imidazopyrimidine derivatives having sulfur-containing phenyl and pyridyl substituents 先正达参股股份有限公司 2023-05-23 CN disclosed
CN-115551857-A Imidazopyrimidinone compounds as pesticides 巴斯夫欧洲公司 2022-12-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250026757-A1 Bicyclic Compounds for the Control of Invertebrate Pests DDT, BROX, CYCS SMN1; SMN2 2518/4885MAPT 3996/4885ALDH1A1 2188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.