Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | PPM1B | O75688 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25694068 | 1.00 | CHRNB2 (0.47) | CHRNB2CHRNA5CHRNA7CHRNA4PPM1B | |
| SCHEMBL17505922 | 0.95 | CHRNB2 (0.43) | CHRNB2CHRNA5CHRNA7CHRNA4PPM1B | |
| SCHEMBL9994588 | 0.79 | MGLL (0.40) | PDK2IRAK4 | |
| SCHEMBL9994585 | 0.77 | MGLL (0.41) | PDK2IRAK4 | |
| SCHEMBL18014832 | 0.77 | PDK2 (0.40) | MAPK1PDK2IRAK4 | |
| SCHEMBL26507782 | 0.76 | ALPI (0.44) | PDK2IRAK4 | |
| SCHEMBL2366102 | 0.75 | PPM1B (0.46) | CHRNB2CHRNA5CHRNA7CHRNA4PPM1B | |
| SCHEMBL2366108 | 0.75 | PPM1B (0.46) | CHRNB2CHRNA5CHRNA7CHRNA4PPM1B | |
| SCHEMBL9453170 | 0.75 | PPM1B (0.46) | CHRNB2CHRNA5CHRNA7CHRNA4PPM1B | |
| SCHEMBL6920902 | 0.75 | PDK2 (0.43) | KMT2APDK2IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066296-A1 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF | ALEXION PHARMACEUTICALS, INC. (US) | 2025-02-27 | — | — | US | disclosed |
| EP-4448490-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF | Alexion Pharmaceuticals, Inc. (US) | 2024-10-23 | — | — | EP | disclosed |
| US-11814363-B2 | Morphic forms of danicopan | ACHILLION PHARMACEUTICALS, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| WO-2023114200-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF | ALEXION PHARMACEUTICALS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023114200-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF | ALEXION PHARMACEUTICALS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| US-20230094124-A1 | MORPHIC FORMS OF DANICOPAN | ACHILLION PHARMACEUTICALS, INC. (US) | 2023-03-30 | — | — | US | disclosed |
| EP-3847174-A1 | MORPHIC FORMS OF COMPLEMENT FACTOR D INHIBITORS | Achillion Pharmaceuticals, Inc. (US) | 2021-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066296-A1 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF | CFD, CFH, CFB | CHRNB2 4837/4885CHRNA5 4874/4885CHRNA7 4869/4885 |
| US-20230094124-A1 | MORPHIC FORMS OF DANICOPAN | CFD, CFH, C9 | CHRNB2 3892/4885CHRNA5 4679/4885CHRNA7 4515/4885 |
| US-11814363-B2 | Morphic forms of danicopan | CFD, CFH, C9 | CHRNB2 4000/4885CHRNA5 4568/4885CHRNA7 4464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.