Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 4/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3948790 | 1.00 | HSD11B1 (0.45) | HSD11B1PSMB5RARBLTB4R2BRS3 | |
| SCHEMBL3952262 | 0.90 | HSD11B1 (0.42) | HSD11B1PSMB5RARBLTB4R2BRS3 | |
| SCHEMBL1345833 | 0.86 | HSD11B1 (0.48) | HSD11B1PSMB5RARBLTB4R2BRS3 | |
| SCHEMBL258162 | 0.86 | HSD11B1 (0.48) | HSD11B1RARBALDH1A1HPGDHSD17B10 | |
| SCHEMBL12638249 | 0.86 | HSD11B1 (0.48) | HSD11B1RARBALDH1A1HPGDHSD17B10 | |
| SCHEMBL4883476 | 0.84 | SKP2 (0.36) | HSD11B1PSMB5RARBLTB4R2ALDH1A1 | |
| SCHEMBL2539038 | 0.84 | CA2 (0.44) | HSD11B1BCHEALDH1A1HPGDHSD17B10 | |
| SCHEMBL14594235 | 0.84 | CA2 (0.44) | HSD11B1BCHEALDH1A1HPGDHSD17B10 | |
| SCHEMBL17366495 | 0.83 | HSD11B1 (0.49) | HSD11B1PSMB5RARBLTB4R2BRS3 | |
| SCHEMBL13422650 | 0.83 | HSD11B1 (0.46) | HSD11B1RARBALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003289-B2 | Ferrocene containing photoconductors | XEROX CORPORATION (US) | 2011-08-23 | — | — | US | claimed |