SCHEMBL258162

SCHEMBL258162

CCCCc1ccc(N(c2ccc(-c3ccc(-c4ccc(N(c5ccc(CCCC)cc5)c5ccccc5C)cc4)cc3)cc2)c2ccccc2C)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.48
RARB P10826 7/20 0.44
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
HSD17B10 Q99714 2/20 0.40
ALDH1A1 P00352 2/20 0.40
NISCH Q9Y2I1 1/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
SKP2 Q13309 1/20 0.39
MEN1 O00255 1/20 0.39
RARA P10276 1/20 0.39
MAPT P10636 1/20 0.39
MTOR P42345 1/20 0.39
KMT2A Q03164 1/20 0.39
CNR2 P34972 1/20 0.38
CTSV O60911 1/20 0.38
CTSL P07711 1/20 0.38
CHRM2 P08172 1/20 0.38
HTR1A P08908 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12638249 1.00 HSD11B1 (0.48) HSD11B1RARBCA1CA2HSD17B10
SCHEMBL13422650 0.97 HSD11B1 (0.46) HSD11B1RARBCA1CA2HSD17B10
SCHEMBL12533893 0.97 HSD11B1 (0.48) HSD11B1RARBCA1CA2HSD17B10
SCHEMBL919859 0.95 HSD11B1 (0.47) HSD11B1RARBCA1CA2HSD17B10
SCHEMBL2539038 0.95 CA2 (0.44) HSD11B1CA1CA2HSD17B10ALDH1A1
SCHEMBL14594235 0.95 CA2 (0.44) HSD11B1CA1CA2HSD17B10ALDH1A1
SCHEMBL12779463 0.94 HSD11B1 (0.43) HSD11B1RARBCA1CA2HSD17B10
SCHEMBL20057200 0.93 HSD11B1 (0.43) HSD11B1RARBCA1CA2HSD17B10
SCHEMBL24568479 0.87 LPL (0.46) HSD11B1CA2HSD17B10ALDH1A1CHRM2
SCHEMBL2362998 0.86 HSD11B1 (0.45) HSD11B1RARBHSD17B10ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 925 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2270601-B1 PHOTOCONDUCTOR CONTAINING A CHARGE TRANSPORT LAYER WITH A FLUORINATED POLYMER AND A CORE SHELL COMPONENT XEROX CORP (US) 2017-11-29 EP claimed
EP-2270600-B1 Core shell photoconductors XEROX CORP (US) 2017-04-19 EP claimed
US-9411251-B2 Photoconductor containing a charge transport layer having an arylamine hole transport material XEROX CORPORATION (US) 2016-08-09 US claimed
EP-2290452-B1 POSS melamine overcoated photoconductors XEROX CORP (US) 2016-06-01 EP claimed
US-20150037715-A1 PHOTOCONDUCTOR CONTAINING A CHARGE TRANSPORT LAYER HAVING AN ARYLAMINE HOLE TRANSPORT MATERIAL XEROX CORPORATION (US) 2015-02-05 US claimed
US-8765339-B2 Imaging member layers XEROX CORPORATION (US) 2014-07-01 US claimed
US-20140065533-A1 IMAGING MEMBER LAYERS XEROX CORPORATION (US) 2014-03-06 US claimed
EP-2224288-B1 PHOTOCONDUCTORS COMPRISING EPOXY CARBOXYL RESIN MIXTURE HOLE BLOCKING LAYER XEROX CORP (US) 2013-10-16 EP claimed
US-8535859-B2 Photoconductors containing biaryl polycarbonate charge transport layers XEROX CORPORATION (US) 2013-09-17 US claimed
US-8481237-B2 Photoconductor overcoat layer XEROX CORPORATION (US) 2013-07-09 US claimed
US-20070292789-A1 Polyphenyl ether containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292787-A1 Flexible imaging member such as a belt including a photogenerating layer and a charge transport mixture of an antioxidant and a polyphenyl thioether that may contain phenoxy groups, e.g., 1-phenoxy-3-[[3-(phenylthio)phenyl]thio]benzene; increased surface hardness, wear resistance and solvent resistance XEROX CORPORATION 2007-12-20 US claimed
US-20070292791-A1 Polyphenyl thioether containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292785-A1 Polyphenyl thioether phosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292782-A1 Polyphenyl ether phosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292793-A1 Thiophosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070254226-A1 Imaging member XEROX CORPORATION 2007-11-01 US claimed
EP-1850185-A2 Imaging Member Xerox Corporation (US) 2007-10-31 EP claimed
EP-0029703-B1 ELECTROPHOTOGRAPHIC IMAGING MEMBER XEROX CORPORATION (US) 1984-03-21 EP claimed
US-4273846-A Imaging member having a charge transport layer of a terphenyl diamine and a polycarbonate resin XEROX CORPORATION (US) 1981-06-16 US claimed