SCHEMBL23630170

SCHEMBL23630170

CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CN)C(=O)OC(=O)C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ QRFPR Q96P65 5/20 0.45
▸ MME P08473 1/20 0.44
▸ ANPEP P15144 1/20 0.44
▸ LTA4H P09960 1/20 0.43
▸ CCKAR P32238 1/20 0.42
▸ CCKBR P32239 1/20 0.42
▸ POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL23630172 0.88 LTA4H (0.53) QRFPRLTA4H
Trifluoroacetic Acid SCHEMBL23630169 0.88 LTA4H (0.53) QRFPRLTA4H
SCHEMBL5507650 0.85 LTA4H (0.58) QRFPRLTA4H
SCHEMBL23629872 0.81 OPRD1 (0.45) QRFPR
SCHEMBL28569722 0.79 CTSC (0.48) POLB
SCHEMBL11309774 0.78 MME (0.50) MMEANPEPLTA4HPOLB
SCHEMBL30051473 0.78 LTA4H (0.64) LTA4H
SCHEMBL11225559 0.77 LTA4H (0.54) LTA4H
SCHEMBL28558742 0.77 MME (0.38) MMEANPEPLTA4HPOLB
SCHEMBL24191702 0.77 LTA4H (0.52) ANPEPLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12370263-B2 Cyclic dinucleotide derivative based antibody-drug conjugates DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-07-29 — — US disclosed
EP-4524154-A2 ANTIBODY-DRUG CONJUGATES OF CYCLIC DINUCLEOTIDE DERIVATIVES Daiichi Sankyo Company, Limited (JP) 2025-03-19 — — EP disclosed
EP-3848054-B1 ANTIBODY-DRUG CONJUGATES OF CYCLIC DINUCLEOTIDE DERIVATIVES DAIICHI SANKYO CO LTD (JP) 2025-01-29 — — EP disclosed
US-20240293567-A1 NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF DAIICHI SANKYO COMPANY, LIMITED (JP) 2024-09-05 — — US disclosed
US-20220008549-A1 NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF DAIICHI SANKYO COMPANY, LIMITED (JP) 2022-01-13 — — US disclosed
EP-3848054-A1 NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF Daiichi Sankyo Company, Limited (JP) 2021-07-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12370263-B2 Cyclic dinucleotide derivative based antibody-drug conjugates STING1, CGAS, CDA QRFPR 984/4885MME 3130/4885ANPEP 880/4885
US-20220008549-A1 NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF STING1, CGAS, TLR9 QRFPR 900/4885MME 2993/4885ANPEP 918/4885
US-20240293567-A1 NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF STING1, CGAS, TLR9 QRFPR 900/4885MME 2993/4885ANPEP 918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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