Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28569722 | 0.78 | CTSC (0.48) | ACEECE1POLBCTRB1 | |
| SCHEMBL23630170 | 0.77 | QRFPR (0.45) | MMEANPEPLTA4HPOLB | |
| SCHEMBL28555237 | 0.73 | ACE (0.40) | LTA4HFNTAFNTBACETACR3 | |
| SCHEMBL29051005 | 0.70 | ACE (0.41) | ACE | |
| SCHEMBL30051473 | 0.69 | LTA4H (0.64) | LTA4HFNTAFNTB | |
| SCHEMBL30050877 | 0.69 | LTA4H (0.60) | MMEANPEPLTA4HFNTAFNTB | |
| SCHEMBL11309774 | 0.68 | MME (0.50) | MMEANPEPLTA4HFNTAFNTB | |
| SCHEMBL11225559 | 0.68 | LTA4H (0.54) | LTA4H | |
| Trifluoroacetic Acid SCHEMBL31139218 | 0.68 | ACE (0.63) | MMEACEECE1 | |
| Trifluoroacetic Acid SCHEMBL28569723 | 0.68 | ACE (0.63) | MMEACEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112714649-B | Cyclic dinucleotide derivatives and antibody drug conjugates thereof | 第一三共株式会社 | 2024-07-02 | — | — | CN | disclosed |
| CN-112714649-A | Novel cyclic dinucleotide derivatives and antibody drug conjugates thereof | 第一三共株式会社 | 2021-04-27 | — | — | CN | disclosed |