Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 7/20 | 0.51 |
| ▸ | ANPEP | P15144 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23630457 | 0.87 | POLB (0.61) | POLBALDH1A1KMT2ALMNAMMP2 | |
| SCHEMBL6097783 | 0.87 | POLB (0.61) | POLBALDH1A1KMT2ALMNAMMP2 | |
| SCHEMBL3832846 | 0.87 | POLB (0.61) | POLBALDH1A1KMT2ALMNAMMP2 | |
| Lithium Ion SCHEMBL23630310 | 0.85 | POLB (0.52) | POLBALDH1A1KMT2ALMNAMMP2 | |
| SCHEMBL3831709 | 0.85 | POLB (0.56) | POLBALDH1A1KMT2ALMNAMMP2 | |
| SCHEMBL3831713 | 0.85 | POLB (0.52) | POLBALDH1A1KMT2ALMNAMMP2 | |
| SCHEMBL23630483 | 0.83 | KMT2A (0.50) | POLBALDH1A1KMT2ALMNAMMP2 | |
| SCHEMBL541908 | 0.83 | ALDH1A1 (0.76) | POLBALDH1A1KMT2ALMNAMMP2 | |
| SCHEMBL541907 | 0.83 | ALDH1A1 (0.76) | POLBALDH1A1KMT2ALMNAMMP2 | |
| SCHEMBL29948324 | 0.83 | ALDH1A1 (0.76) | POLBALDH1A1KMT2ALMNAMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4087650-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | UNIWERSYTET JAGIELLONSKI (PL) | 2022-11-16 | — | — | EP | claimed |
| EP-4087651-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | UNIWERSYTET JAGIELLONSKI (PL) | 2022-11-16 | — | — | EP | claimed |
| EP-4087650-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | UNIWERSYTET JAGIELLONSKI (PL) | 2022-11-16 | — | — | EP | disclosed |
| EP-4087651-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | UNIWERSYTET JAGIELLONSKI (PL) | 2022-11-16 | — | — | EP | disclosed |
| WO-2021141506-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | Uniwersytet Jagielloński (PL) | 2021-07-15 | — | — | WO | disclosed |
| WO-2021141507-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A3, THEIR SYNTHESIS AND USE | Uniwersytet Jagielloński (PL) | 2021-07-15 | — | — | WO | disclosed |