Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MMP2 | P08253 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23630457 | 1.00 | POLB (0.61) | POLBMMP2ALDH1A1KMT2ANPSR1 | |
| SCHEMBL3832846 | 1.00 | POLB (0.61) | POLBMMP2ALDH1A1KMT2ANPSR1 | |
| SCHEMBL23630441 | 0.87 | POLB (0.54) | POLBMMP2ALDH1A1KMT2ANPSR1 | |
| SCHEMBL11458196 | 0.86 | POLB (0.58) | POLBMMP2ALDH1A1KMT2ANPSR1 | |
| SCHEMBL21551179 | 0.86 | POLB (0.58) | POLBMMP2ALDH1A1KMT2ANPSR1 | |
| SCHEMBL9215368 | 0.86 | POLB (0.58) | POLBMMP2ALDH1A1KMT2ANPSR1 | |
| SCHEMBL9379038 | 0.86 | POLB (0.58) | POLBMMP2ALDH1A1KMT2ANPSR1 | |
| SCHEMBL11459546 | 0.86 | POLB (0.58) | POLBMMP2ALDH1A1KMT2ANPSR1 | |
| SCHEMBL9215362 | 0.86 | POLB (0.58) | POLBMMP2ALDH1A1KMT2ANPSR1 | |
| SCHEMBL11459547 | 0.86 | POLB (0.58) | POLBMMP2ALDH1A1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021141507-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A3, THEIR SYNTHESIS AND USE | Uniwersytet Jagielloński (PL) | 2021-07-15 | — | — | WO | disclosed |
| WO-2021141506-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | Uniwersytet Jagielloński (PL) | 2021-07-15 | — | — | WO | disclosed |
| US-7109352-B2 | Process for producing optically active amino acid derivatives | KANEKA CORPORATION (JP) | 2006-09-19 | — | — | US | disclosed |
| US-20050143586-A1 | Process for producing optically active amino acid derivatives | KANEKA CORPORATION (JP) | 2005-06-30 | — | — | US | disclosed |
| US-6720449-B2 | N-PROTECTING AN OPTICALLY ACTIVE 3-HALOALANINE DERIVATIVE FOLLOWED BY CYCLIZATION FOR AZIRIDINE-2-CARBOXYLIC ACID DERIVATIVES | KANEKA CORPORATION (JP) | 2004-04-13 | — | — | US | disclosed |
| US-20030032814-A1 | Process for preparing optically active amino acid derivatives | KANEKA CORPORATION (JP) | 2003-02-13 | — | — | US | disclosed |
| EP-1179530-A1 | PROCESSES FOR PREPARING OPTICALLY ACTIVE AMINO ACID DERIVATIVES | Kaneka Corporation (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0193904-B1 | AMINO ACID DERIVATIVES AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
| US-4743614-A | RESTORATIVE PROPERTIES INC IMMUNODEFICIENT HOSTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-10 | — | — | US | disclosed |
| EP-0193904-A2 | Amino acid derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143586-A1 | Process for producing optically active amino acid derivatives | NPEPPS, AAAS, DDC | POLB 3616/4885MMP2 3277/4885ALDH1A1 1582/4885 |
| US-20030032814-A1 | Process for preparing optically active amino acid derivatives | NPEPPS, AAAS, DDC | POLB 3399/4885MMP2 3631/4885ALDH1A1 1618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.