Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | MMP2 | P08253 | 7/20 | 0.69 |
| ▸ | ANPEP | P15144 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541907 | 1.00 | ALDH1A1 (0.76) | ALDH1A1KMT2AMMP2ANPEPLMNA | |
| SCHEMBL29948324 | 1.00 | ALDH1A1 (0.76) | ALDH1A1KMT2AMMP2ANPEPLMNA | |
| SCHEMBL8106846 | 0.88 | KMT2A (0.64) | ALDH1A1KMT2AMMP2ANPEPLMNA | |
| SCHEMBL21551113 | 0.88 | KMT2A (0.64) | ALDH1A1KMT2AMMP2ANPEPLMNA | |
| SCHEMBL2227030 | 0.88 | KMT2A (0.64) | ALDH1A1KMT2AMMP2ANPEPLMNA | |
| SCHEMBL12317084 | 0.88 | ALDH1A1 (0.64) | ALDH1A1KMT2AMMP2ANPEPLMNA | |
| SCHEMBL23630362 | 0.87 | KMT2A (0.59) | ALDH1A1KMT2AMMP2ANPEPLMNA | |
| SCHEMBL1734643 | 0.86 | MMP2 (0.68) | ALDH1A1KMT2AMMP2ANPEP | |
| SCHEMBL1734641 | 0.86 | MMP2 (0.68) | ALDH1A1KMT2AMMP2ANPEP | |
| SCHEMBL2771228 | 0.85 | ALDH1A1 (0.72) | ALDH1A1KMT2AMMP2ANPEPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230069886-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A3, THEIR SYNTHESIS AND USE | UNIWERSYTET JAGIELLONSKI (PL) | 2023-03-09 | — | — | US | disclosed |
| US-20230039836-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A3, THEIR SYNTHESIS AND USE | UNIWERSYTET JAGIELLONSKI (PL) | 2023-02-09 | — | — | US | disclosed |
| EP-4087651-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | UNIWERSYTET JAGIELLONSKI (PL) | 2022-11-16 | — | — | EP | disclosed |
| EP-4087650-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | UNIWERSYTET JAGIELLONSKI (PL) | 2022-11-16 | — | — | EP | disclosed |
| EP-2415766-A1 | METHOD FOR MANUFACTURING BENZODIAZEPINE DERIVATIVE | Zeria Pharmaceutical Co., Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20120010401-A1 | METHOD FOR MANUFACTURING 1,5-BENZODIAZEPINE DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2012-01-12 | — | — | US | disclosed |
| US-20120010401-A1 | METHOD FOR MANUFACTURING 1,5-BENZODIAZEPINE DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2012-01-12 | — | — | US | disclosed |
| US-20120010401-A1 | METHOD FOR MANUFACTURING 1,5-BENZODIAZEPINE DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010401-A1 | METHOD FOR MANUFACTURING 1,5-BENZODIAZEPINE DERIVATIVE | GABRA5, CYP3A5, GABRA1 | ALDH1A1 372/4885KMT2A 883/4885MMP2 4450/4885 |
| US-20230069886-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A3, THEIR SYNTHESIS AND USE | PDIA3, PDIA5, PDIA6 | ALDH1A1 783/4885KMT2A 4568/4885MMP2 1428/4885 |
| US-20230039836-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A3, THEIR SYNTHESIS AND USE | PDIA3, PDIA5, PDIA6 | ALDH1A1 509/4885KMT2A 4490/4885MMP2 1443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.