SCHEMBL23630880

SCHEMBL23630880

c1ccc2c(c1)oc1c2ccc2c3ccccc3c3ncccc3c21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
JAK2 O60674 1/20 0.42
ZAP70 P43403 1/20 0.42
SYK P43405 1/20 0.42
KDM4E B2RXH2 4/20 0.42
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
LIMK1 P53667 1/20 0.41
LMNA P02545 4/20 0.40
NPC1 O15118 3/20 0.40
RAB9A P51151 2/20 0.40
USP2 O75604 1/20 0.40
HTT P42858 1/20 0.40
NCOA1 Q15788 2/20 0.40
MAPT P10636 5/20 0.38
TSHR P16473 2/20 0.38
DRD4 P21917 1/20 0.37
HPGD P15428 3/20 0.37
CASP3 P42574 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24039790 0.84 AHR (0.46) KMT2AMEN1JAK2ZAP70SYK
SCHEMBL14476381 0.84 AHR (0.46) KMT2AMEN1JAK2ZAP70SYK
SCHEMBL31668235 0.84 AHR (0.46) KMT2AMEN1JAK2ZAP70SYK
SCHEMBL28213040 0.83 KMT2A (0.43) KMT2AMEN1JAK2ZAP70SYK
SCHEMBL26445289 0.79 HSP90AA1 (0.42) KMT2AMEN1KDM4EALDH1A1SMN1; SMN2
SCHEMBL2620740 0.78 MAOA (0.44) KMT2AMEN1KDM4EALDH1A1SMN1; SMN2
SCHEMBL29385940 0.78 MAOA (0.44) KMT2AMEN1KDM4EALDH1A1SMN1; SMN2
SCHEMBL24791088 0.78 ALOX5 (0.42) KMT2AMEN1KDM4EALDH1A1SMN1; SMN2
SCHEMBL30171460 0.77 KDM4E (0.50) KMT2AMEN1KDM4EALDH1A1SMN1; SMN2
SCHEMBL24290365 0.75 JAK2 (0.37) KMT2AMEN1JAK2ZAP70SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12201013-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-01-14 US disclosed
US-20210217970-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-07-15 US disclosed
US-20210217970-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-07-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210217970-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EPCAM, OR10J3 KMT2A 2498/4885MEN1 3073/4885JAK2 2212/4885
US-12201013-B2 Organic electroluminescent materials and devices L1CAM, SOD1, EPCAM KMT2A 3742/4885MEN1 1926/4885JAK2 2390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.