Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CTH | P32929 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22026735 | 0.92 | FAAH (0.52) | FAAHSMN1; SMN2HPGDEGLN1ALDH1A1 | |
| SCHEMBL6576933 | 0.89 | FAAH (0.49) | FAAHSMN1; SMN2HPGDEGLN1ALDH1A1 | |
| SCHEMBL23643341 | 0.81 | FAAH (0.42) | FAAHSMN1; SMN2HPGDALDH1A1USP2 | |
| SCHEMBL5194280 | 0.78 | FAAH (0.53) | FAAHSMN1; SMN2HPGDALDH1A1USP2 | |
| SCHEMBL16812084 | 0.78 | PAM (0.47) | FAAHSMN1; SMN2HPGDALDH1A1USP2 | |
| SCHEMBL25575163 | 0.77 | EGLN1 (0.37) | FAAHHPGDEGLN1ALDH1A1HSD17B10 | |
| SCHEMBL13793360 | 0.76 | POLB (0.46) | FAAHSMN1; SMN2HPGDALDH1A1USP2 | |
| SCHEMBL21814409 | 0.76 | ALDH1A1 (0.55) | SMN1; SMN2HPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL3342301 | 0.73 | MGAM (0.46) | FAAHSMN1; SMN2HPGDALDH1A1USP2 | |
| SCHEMBL15945454 | 0.73 | MGAM (0.46) | FAAHSMN1; SMN2HPGDALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210214374-A1 | COMPOUNDS AND COMPOSITIONS FOR OCULAR DELIVERY | Graybug Vision, Inc. (US) | 2021-07-15 | — | — | US | disclosed |
| US-20210214374-A1 | COMPOUNDS AND COMPOSITIONS FOR OCULAR DELIVERY | Graybug Vision, Inc. (US) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214374-A1 | COMPOUNDS AND COMPOSITIONS FOR OCULAR DELIVERY | KDR, RB1, PDE6C | FAAH 2594/4885SMN1; SMN2 700/4885HPGD 1104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.