Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.49 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARD | Q03181 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stearic Acid SCHEMBL2352469 | 0.92 | PLA2G2A (0.51) | PLA2G2APLA2G4AGPR84PPARGPPARD | |
| Buformin SCHEMBL17107816 | 0.85 | EPHX2 (0.42) | PLA2G2APLA2G4AALOX15EPHX2 | |
| Hexane SCHEMBL27897485 | 0.84 | GNAI3 (0.46) | TSHRALDH1A1MEN1KMT2A | |
| Polihexanide SCHEMBL27900001 | 0.82 | SPHK1 (0.49) | PLA2G2AMEN1KMT2A | |
| Acetic Acid SCHEMBL28642374 | 0.82 | EPHX1 (0.48) | PLA2G2A | |
| Stearic Acid SCHEMBL15058500 | 0.82 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL17234293 | 0.82 | PRMT1 (0.44) | PLA2G4AHDAC11TSHRFABP4SLC22A6 | |
| Nonanoate SCHEMBL28606614 | 0.82 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL27605584 | 0.82 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Buformin SCHEMBL10448569 | 0.81 | SPHK1 (0.40) | ALOX15EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109502593-B | Production method of high-purity quartz sand with low hydroxyl and low gas-liquid inclusion | 临沂昊泉硅业科技有限公司 | 2021-10-08 | — | — | CN | claimed |
| CN-109553905-B | Preparation method of reinforced polymethacrylimide foam composite material | 浙江中科恒泰新材料科技有限公司 | 2021-05-04 | — | — | CN | claimed |
| CN-109880503-B | Preparation method of low-temperature-resistant leather finishing agent | 上海皇宇科技发展有限公司 | 2021-04-13 | — | — | CN | claimed |
| CN-109280306-B | Preparation method of polymethacrylimide composite foam conductive wave-absorbing material | 浙江中科恒泰新材料科技有限公司 | 2021-04-13 | — | — | CN | claimed |
| CN-108570207-B | Preparation method of high-strength automobile new material | 博兴融智科技创新发展有限公司 | 2020-12-15 | — | — | CN | claimed |
| CN-108485219-B | Preparation method of bio-based wood-plastic composite new material | 安徽中科达美新材料科技有限公司 | 2020-12-11 | — | — | CN | claimed |
| CN-108751210-B | Calcining method of high-purity quartz sand | 新疆能源（集团）晶拓科技材料有限责任公司 | 2020-10-09 | — | — | CN | claimed |
| CN-109664566-B | Light broadband wave-absorbing composite material with multilayer structure and preparation method thereof | 浙江中科恒泰新材料科技有限公司 | 2020-09-15 | — | — | CN | claimed |
| CN-110585084-A | Blend liquid of Chinese herbal medicine mask powder and preparation method and application thereof | 罗梅英 | 2019-12-20 | — | — | CN | claimed |
| CN-110585041-A | Preparation method of blend liquid of Chinese herbal medicine mask powder | 罗梅英 | 2019-12-20 | — | — | CN | claimed |
| CN-109280306-A | A kind of preparation method of Polymethacrylimide composite foam conduction absorbing material | 浙江中科恒泰新材料科技有限公司 | 2019-01-29 | — | — | CN | claimed |
| CN-109111837-A | A kind of preparation method of low temperature resistant leather finishing agent | 宁波高新区诠宝绶新材料科技有限公司 | 2019-01-01 | — | — | CN | claimed |
| CN-108926586-A | The preparation method of Korean red ginseng broken wall ultrafine powder particle | 天参密码科技股份有限公司 | 2018-12-04 | — | — | CN | claimed |
| CN-108869233-A | A kind of small-sized pressure stabilizing long axis Fire Fighting Pumps using novel coolant | 贝德科技有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-108751210-A | A kind of method for calcinating of glass sand | 新疆能源（集团）晶拓科技材料有限责任公司 | 2018-11-06 | — | — | CN | claimed |
| CN-108690510-A | A kind of preparation method of leather gloss agent | 张玲 | 2018-10-23 | — | — | CN | claimed |
| CN-108587398-A | A kind of preparation method of the fluorine-containing insulated paint of environment-friendly type | 张玲 | 2018-09-28 | — | — | CN | claimed |
| CN-108520851-A | A kind of logical device side wall etching machine using refractory seals new material | 丁爱琴 | 2018-09-11 | — | — | CN | claimed |
| CN-108520950-A | A kind of production method of electrode new material for electric vehicle | 刘文会 | 2018-09-11 | — | — | CN | claimed |
| CN-108485219-A | A kind of preparation method of biology base wood plastics composite new material | 张玲 | 2018-09-04 | — | — | CN | claimed |