Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23633027 | 1.00 | PIM1 (0.32) | PIM1PIM2CLCN2HPGD | |
| SCHEMBL29593184 | 1.00 | PIM1 (0.32) | PIM1PIM2CLCN2HPGD | |
| SCHEMBL23633049 | 0.80 | CLCN2 (0.37) | PIM1PIM2CLCN2HPGD | |
| SCHEMBL29593979 | 0.80 | CLCN2 (0.37) | PIM1PIM2CLCN2HPGD | |
| SCHEMBL25891666 | 0.77 | — | — | |
| SCHEMBL23633041 | 0.72 | ALDH1A1 (0.32) | — | |
| SCHEMBL21623040 | 0.72 | ALDH1A1 (0.32) | — | |
| SCHEMBL29593843 | 0.72 | ALDH1A1 (0.32) | — | |
| SCHEMBL23633015 | 0.70 | ALDH1A1 (0.46) | CLCN2HPGD | |
| SCHEMBL21386690 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502556-A | Biphenyl fluoro double bond derivative and preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021254005-A1 | IMMUNOSUPPRESSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海和誉生物医药科技有限公司 | 2021-12-23 | — | — | WO | disclosed |
| WO-2021139647-A1 | BIPHENYL FLUORINE DOUBLE BOND DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 上海和誉生物医药科技有限公司 | 2021-07-15 | — | — | WO | disclosed |