Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23633041 | 1.00 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL21623040 | 1.00 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL29945088 | 0.84 | APLNR (0.30) | — | |
| SCHEMBL28863825 | 0.84 | APLNR (0.30) | — | |
| SCHEMBL28863827 | 0.84 | APLNR (0.30) | — | |
| SCHEMBL25891666 | 0.83 | — | — | |
| SCHEMBL24311194 | 0.80 | PDCD1 (0.38) | — | |
| SCHEMBL30340515 | 0.74 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL21622907 | 0.74 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL23633030 | 0.72 | PIM1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12473282-B2 | Biphenyl fluorine double bond derivative, preparation method therefor, and pharmaceutical application thereof | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2025-11-18 | — | — | US | disclosed |
| US-20230014651-A1 | BIPHENYL FLUORINE DOUBLE BOND DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2023-01-19 | — | — | US | disclosed |
| EP-4089091-A1 | BIPHENYL FLUORINE DOUBLE BOND DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2022-11-16 | — | — | EP | disclosed |
| CN-114502556-A | Biphenyl fluoro double bond derivative and preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12473282-B2 | Biphenyl fluorine double bond derivative, preparation method therefor, and pharmaceutical application thereof | PDCD1, CD274, PDCD1LG2 | ALDH1A1 171/4885 |
| US-20230014651-A1 | BIPHENYL FLUORINE DOUBLE BOND DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | PDCD1, CD274, PDCD1LG2 | ALDH1A1 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.