SCHEMBL23633151

SCHEMBL23633151

CCCCCc1cccnc1CO

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.47
ALDH1A1 P00352 1/20 0.47
LIPG Q9Y5X9 1/20 0.46
ALOX5 P09917 2/20 0.45
PTGS2 P35354 1/20 0.45
TDP1 Q9NUW8 2/20 0.42
PPARA Q07869 2/20 0.40
BID P55957 3/20 0.40
MCL1 Q07820 3/20 0.40
BCL2L1 Q07817 2/20 0.40
BAK1 Q16611 2/20 0.40
KAT8 Q9H7Z6 2/20 0.40
PPARG P37231 1/20 0.40
EP300 Q09472 1/20 0.40
KAT2A Q92830 1/20 0.40
KAT2B Q92831 1/20 0.40
KAT5 Q92993 1/20 0.40
SAE1 Q9UBE0 1/20 0.40
GCGR P47871 1/20 0.39
KCNH2 Q12809 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11198582 0.98 LIPG (0.49) L3MBTL1ALDH1A1LIPGALOX5PTGS2
SCHEMBL19444397 0.95 L3MBTL1 (0.48) L3MBTL1ALDH1A1LIPGALOX5PTGS2
SCHEMBL5108741 0.87 L3MBTL1 (0.52) L3MBTL1ALDH1A1MEN1MAPTHTT
SCHEMBL461554 0.87 TDP1 (0.50) L3MBTL1LIPGALOX5PTGS2TDP1
SCHEMBL29031761 0.86 TDP1 (0.49) L3MBTL1LIPGALOX5PTGS2TDP1
SCHEMBL1425613 0.86 TDP1 (0.49) L3MBTL1LIPGALOX5PTGS2TDP1
Hydrogen Sulfide SCHEMBL28566437 0.86 TDP1 (0.49) L3MBTL1LIPGALOX5PTGS2TDP1
SCHEMBL17708698 0.86 TDP1 (0.44) L3MBTL1LIPGALOX5PTGS2TDP1
SCHEMBL23768448 0.86 TDP1 (0.49) L3MBTL1LIPGALOX5PTGS2TDP1
SCHEMBL28163513 0.86 TDP1 (0.49) L3MBTL1LIPGALOX5PTGS2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021141165-A1 AMINO ALCOHOL-BORON-BINOL COMPOSITE AND METHOD FOR PREPARING OPTICALLY ACTIVE AMINO ALCOHOL DERIVATIVE USING SAME (주)분자와물질 2021-07-15 WO disclosed