SCHEMBL23633192

SCHEMBL23633192

O=C(O)Cc1cn2cc(Br)ccc2n1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
KDM4E B2RXH2 3/20 0.56
POLB P06746 3/20 0.56
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
RAB9A P51151 4/20 0.55
NPC1 O15118 3/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
RXFP1 Q9HBX9 2/20 0.55
PIK3CG P48736 1/20 0.49
PKM P14618 1/20 0.46
METTL3 Q86U44 2/20 0.46
TP53 P04637 1/20 0.45
TSHR P16473 1/20 0.45
CLK1 P49759 1/20 0.42
DYRK1A Q13627 1/20 0.42
MAP3K5 Q99683 1/20 0.42
DRD2 P14416 1/20 0.41
DRD4 P21917 1/20 0.41
DRD3 P35462 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1500340 0.86 RAB9A (0.51) ALDH1A1KDM4EPOLBTDP1L3MBTL1
SCHEMBL21301424 0.82 KDM4E (0.66) ALDH1A1KDM4EPOLBTDP1L3MBTL1
SCHEMBL15068553 0.81 KDM4E (0.68) ALDH1A1KDM4EPOLBTDP1L3MBTL1
SCHEMBL4822612 0.80 KDM4E (0.47) ALDH1A1KDM4EPOLBTDP1L3MBTL1
SCHEMBL9570252 0.80 PIK3CG (0.55) ALDH1A1KDM4ERAB9ANPC1SMN1; SMN2
SCHEMBL9598573 0.80 PIK3CG (0.55) ALDH1A1KDM4ERAB9ANPC1SMN1; SMN2
Hydrochloric Acid SCHEMBL27146172 0.79 ALDH1A1 (0.55) ALDH1A1KDM4EPOLBTDP1L3MBTL1
SCHEMBL31528532 0.78 KDM4E (0.69) ALDH1A1KDM4EPOLBTDP1L3MBTL1
SCHEMBL1500381 0.78 RXFP1 (0.45) ALDH1A1KDM4EPOLBTDP1L3MBTL1
SCHEMBL22530986 0.77 KDM4E (0.52) ALDH1A1KDM4EPOLBTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116456817-A Heterocyclic compound and harmful arthropod control composition containing same 住友化学株式会社 2023-07-18 CN disclosed
CN-114981276-A Heterocyclic compound and harmful arthropod control composition containing same 住友化学株式会社 2022-08-30 CN disclosed
WO-2022071428-A1 HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING COMPOSITION INCLUDING SAME 住友化学株式会社 2022-04-07 WO disclosed
WO-2021141106-A1 HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING COMPOSITION INCLUDING SAME 住友化学株式会社 2021-07-15 WO disclosed