Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1500151 | 0.81 | PIK3CG (0.55) | PIK3CGRAB9ANPC1SMN1; SMN2RXFP1 | |
| SCHEMBL9598573 | 0.81 | PIK3CG (0.55) | PIK3CGRAB9ANPC1SMN1; SMN2RXFP1 | |
| SCHEMBL5760557 | 0.81 | PIK3CG (0.55) | PIK3CGRAB9ANPC1SMN1; SMN2RXFP1 | |
| SCHEMBL23633192 | 0.80 | ALDH1A1 (0.56) | PIK3CGRAB9ANPC1SMN1; SMN2RXFP1 | |
| SCHEMBL9570490 | 0.79 | NPC1 (0.50) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL1500197 | 0.79 | PIK3CG (0.51) | PIK3CGRAB9ANPC1SMN1; SMN2RXFP1 | |
| SCHEMBL16797795 | 0.79 | PIK3CG (0.56) | PIK3CGRAB9ANPC1SMN1; SMN2RXFP1 | |
| SCHEMBL1500354 | 0.79 | PIK3CG (0.51) | PIK3CGRAB9ANPC1SMN1; SMN2RXFP1 | |
| SCHEMBL1500340 | 0.78 | RAB9A (0.51) | PIK3CGRAB9ANPC1SMN1; SMN2RXFP1 | |
| SCHEMBL9570213 | 0.78 | KDM4E (0.63) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |
| EP-0555825-A1 | Imidazo(1,2-a)pyridines as angiotensin-II-antagonists | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |