SCHEMBL23633720

SCHEMBL23633720

C=C/C=C\C=C(/C)c1nc(-c2cccc(-c3ccc4c(-c5ccccc5)cccc4c3)c2)nc(-c2cc(-c3ccccc3)cc(-c3ccccc3)c2)n1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 1/20 0.36
HSD17B2 P37059 1/20 0.36
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
SCN5A Q14524 1/20 0.31
SCN9A Q15858 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
TLR8 Q9NR97 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24453087 0.87 CA12 (0.33) HSD17B1HSD17B2CA12CA1CA2
SCHEMBL19053783 0.86 MAPT (0.33) CYP1A2CYP2C9CYP2C19
SCHEMBL19820329 0.86 CYP2C9 (0.33) CA12CA1CA2CA9CYP1A2
SCHEMBL24066720 0.82 CYP11B1 (0.37)
SCHEMBL23759575 0.82 MAPT (0.33) HSD17B1HSD17B2
SCHEMBL25100339 0.81 ALOX5 (0.34)
SCHEMBL19074874 0.81 LMNA (0.37) CYP1A2CYP2C9CYP2C19
SCHEMBL19413625 0.79 DHODH (0.37)
SCHEMBL22308732 0.79 MEN1 (0.43) CYP2C19
SCHEMBL23633698 0.79 HSD17B1 (0.47) HSD17B1HSD17B2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11063226-B1 Organic electronic element comprising compound for organic electronic element and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2021-07-13 US disclosed