SCHEMBL2363384

SCHEMBL2363384

O=C(O)CCNC(=O)Cc1ccc(Cl)cc1-c1ccc(Cl)cc1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GCGR P47871 16/20 0.57
GCG P01275 5/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2362953 0.78 HPGD (0.52) GCGRGCG
SCHEMBL11287245 0.76 CNR1 (0.42) GCGRGCG
SCHEMBL2363580 0.75 GCGR (0.58) GCGRGCG
SCHEMBL14055233 0.74 GCGR (1.00) GCGR
SCHEMBL14057213 0.74 GCGR (1.00) GCGRGCG
SCHEMBL2393525 0.73 PTGDR2 (0.47)
SCHEMBL5429296 0.73 PTGDR2 (0.56)
SCHEMBL2364901 0.73 GCGR (0.52) GCGRGCG
SCHEMBL9890670 0.73 ACLY (0.50) GCGRGCG
SCHEMBL14054861 0.72 GCGR (1.00) GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2349999-A1 ALLOSTERIC PROTEIN KINASE MODULATORS Universität des Saarlandes (DE) 2011-08-03 EP claimed
WO-2010043711-A1 ALLOSTERIC PROTEIN KINASE MODULATORS UNIVERSITAET DES SAARLANDES (DE) 2010-04-22 WO claimed