Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.31 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.31 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2363389 | 0.84 | PKM (0.36) | PKMSCN9AL3MBTL1ALDH1A1CACNA1G | |
| SCHEMBL2363051 | 0.83 | CACNA1G (0.38) | PKMSCN9AL3MBTL1ALDH1A1CACNA1G | |
| SCHEMBL18241099 | 0.83 | NR3C1 (0.35) | PKMSCN9AL3MBTL1ALDH1A1CACNA1G | |
| SCHEMBL2363444 | 0.80 | PKM (0.37) | PKMSCN9AL3MBTL1ALDH1A1CACNA1G | |
| SCHEMBL18241097 | 0.77 | PTGER4 (0.33) | — | |
| SCHEMBL2362832 | 0.75 | NPC1 (0.32) | PKML3MBTL1 | |
| SCHEMBL2362722 | 0.75 | PKM (0.35) | PKMSCN9ACACNA1GCACNA1HCACNA1I | |
| SCHEMBL2363387 | 0.70 | PKM (0.38) | PKMSCN9AL3MBTL1ALDH1A1CACNA1G | |
| SCHEMBL2363049 | 0.69 | CACNA1G (0.39) | PKMSCN9AL3MBTL1ALDH1A1CACNA1G | |
| SCHEMBL13365020 | 0.69 | PKM (0.37) | PKMSCN9AL3MBTL1CACNA1GCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352723-B1 | PESTICIDAL N-ARYL- OR N-HETEROARYL PYRAZOLE CARBOXAMIDE COMPOUNDS | BAYER IP GMBH (DE) | 2016-11-23 | — | — | EP | disclosed |
| EP-2352723-A2 | HALOGEN-SUBSTITUTED COMPOUNDS USED AS PESTICIDES | Bayer CropScience AG (DE) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010051926-A2 | NEW HALOGEN-SUBSTITUTED BONDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-05-14 | — | — | WO | disclosed |