Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | EDNRB | P24530 | 2/20 | 0.33 |
| ▸ | EDNRA | P25101 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | S100A9 | P06702 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17027799 | 0.88 | CNR1 (0.41) | CNR1SPRACLYS100A9STS | |
| SCHEMBL26069625 | 0.78 | ALDH1A1 (0.44) | CNR1 | |
| SCHEMBL16771112 | 0.76 | GABRA1 (0.42) | CNR1SPRS100A9 | |
| Hydrochloric Acid SCHEMBL17061868 | 0.74 | GABRA1 (0.41) | CNR1SPRHTR2C | |
| SCHEMBL24757946 | 0.74 | PTGS2 (0.40) | RAPGEF4FFAR4ACLYPGRFEN1 | |
| SCHEMBL2055455 | 0.74 | FFAR4 (0.39) | RAPGEF4FFAR4ACLYEDNRBEDNRA | |
| SCHEMBL23375706 | 0.74 | TPMT (0.57) | CNR1SPRACLY | |
| SCHEMBL17027820 | 0.73 | TMEM97 (0.52) | HTR2AHTR2C | |
| SCHEMBL788179 | 0.73 | TSHR (0.44) | CNR1RAPGEF4FFAR4ACLYEDNRB | |
| SCHEMBL21462481 | 0.72 | CNR1 (0.33) | CNR1SPRS100A9STSHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107909-B1 | ANTIMITOTIC AMIDES FOR THE TREATMENT OF CANCER AND PROLIFERATIVE DISORDERS | FROST BIOLOGIC INC (US) | 2021-07-14 | — | — | EP | disclosed |