Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 8/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 4/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK3 | P49761 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18996612 | 0.89 | DYRK1A (0.48) | DYRK1AGSK3BABL1F10WNT1 | |
| SCHEMBL23635161 | 0.79 | DYRK1A (0.44) | DYRK1AGSK3BABL1F10WNT1 | |
| SCHEMBL17027809 | 0.76 | DYRK1A (0.42) | DYRK1AGSK3BABL1F10WNT1 | |
| SCHEMBL17027818 | 0.75 | F10 (0.54) | DYRK1AGSK3BF10WNT1CLK2 | |
| SCHEMBL17027858 | 0.75 | DYRK1A (0.47) | DYRK1AGSK3BABL1F10WNT1 | |
| SCHEMBL18979437 | 0.73 | PIK3CA (0.52) | DYRK1AGSK3BF10AKT1PIK3CA | |
| SCHEMBL18979456 | 0.72 | F10 (0.61) | DYRK1AGSK3BF10WNT1CLK2 | |
| SCHEMBL23635162 | 0.71 | DYRK1A (0.34) | DYRK1AGSK3BABL1 | |
| SCHEMBL23635141 | 0.70 | F10 (0.49) | DYRK1AGSK3BF10RPS6KA3WNT1 | |
| SCHEMBL17027778 | 0.70 | DEGS1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107909-B1 | ANTIMITOTIC AMIDES FOR THE TREATMENT OF CANCER AND PROLIFERATIVE DISORDERS | FROST BIOLOGIC INC (US) | 2021-07-14 | — | — | EP | disclosed |