Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 7/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23630440 | 0.78 | LIPE (0.42) | HTR2CLIPEP2RY14F2RADRB3 | |
| SCHEMBL2636716 | 0.71 | LIPE (0.52) | HTR2CLIPEP2RY14F2RADRB3 | |
| SCHEMBL5535882 | 0.70 | LIPE (0.51) | HTR2CLIPEP2RY14F2RADRB3 | |
| SCHEMBL15840446 | 0.68 | EPHX2 (0.62) | P2RY14CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL2297690 | 0.68 | P2RY14 (0.64) | LIPEP2RY14 | |
| SCHEMBL1847401 | 0.67 | HTR2C (0.73) | HTR2C | |
| SCHEMBL6884365 | 0.67 | HTR2C (0.58) | HTR2CLIPEP2RY14KCNH2 | |
| SCHEMBL8456276 | 0.67 | HTR2C (0.46) | HTR2CP2RY14F2RAOC3HSD11B1 | |
| SCHEMBL8456280 | 0.67 | HTR2C (0.46) | HTR2CP2RY14F2RAOC3HSD11B1 | |
| SCHEMBL8456277 | 0.67 | HTR2C (0.46) | HTR2CP2RY14F2RAOC3HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021142420-A1 | PYRAZOLO[1,5-a]PYRIMIDIN-7(4H)-ONE INHIBITORS OF DYNEIN | KAPOOR TARUN M (US) | 2021-07-15 | — | — | WO | disclosed |