Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 4/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20565527 | 0.76 | ARF6 (0.38) | DDR1KDM4EMEN1KMT2AMIF | |
| SCHEMBL20565565 | 0.76 | GRM2 (0.45) | KDM4EMEN1KMT2ACCNCCDK8 | |
| SCHEMBL20565417 | 0.74 | KDM4E (0.38) | DDR1KDM4EMEN1KMT2AMIF | |
| SCHEMBL22001264 | 0.73 | TLR8 (0.35) | KDM4EMEN1KMT2ACCNCCDK8 | |
| SCHEMBL23635316 | 0.72 | ALDH1A1 (0.44) | KDM4EMEN1KMT2ACNR1 | |
| SCHEMBL23635352 | 0.71 | CCNC (0.37) | MEN1KMT2AMIFCCNCCDK8 | |
| SCHEMBL23635317 | 0.70 | GRM2 (0.43) | KDM4EMEN1KMT2AGRM2AOC3 | |
| SCHEMBL23630439 | 0.67 | GRM2 (0.38) | KDM4EMEN1KMT2AGRM2AOC3 | |
| SCHEMBL20565130 | 0.64 | GRM2 (0.38) | KDM4ECDK8GRM2 | |
| SCHEMBL20565526 | 0.64 | GRM2 (0.38) | CCNCCDK8GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021142420-A1 | PYRAZOLO[1,5-a]PYRIMIDIN-7(4H)-ONE INHIBITORS OF DYNEIN | KAPOOR TARUN M (US) | 2021-07-15 | — | — | WO | disclosed |