SCHEMBL23635682

SCHEMBL23635682

Cn1c(C(F)(F)F)c(CCO)c(=O)n(C)c1=O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.39
ITGB1 P05556 2/20 0.33
ITGA4 P13612 2/20 0.33
ITGB7 P26010 2/20 0.33
LMNA P02545 1/20 0.33
ADORA2B P29275 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GLA P06280 1/20 0.33
GAA P10253 2/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25086833 0.84 CYP2C9 (0.34) CYP2C9ADORA2B
SCHEMBL3521446 0.74 GAA (0.41) CYP2C9LMNAADORA2BALDH1A1GAA
SCHEMBL23635607 0.72 HTT (0.37) CYP2C9ITGB1ITGA4ITGB7LMNA
SCHEMBL23635717 0.68 ADORA2A (0.31) CYP2C9LMNACYP2C19ADORA2AMAOB
SCHEMBL23635681 0.66 AOC3 (0.34) CYP2C9KDM4EALDH1A1ADORA2AMAOB
SCHEMBL27935676 0.62 ALDH1A1 (0.39) LMNAADORA2BKDM4EALDH1A1GLA
SCHEMBL3521123 0.61 KDM4E (0.44) LMNAKDM4EALDH1A1GAACYP2D6
SCHEMBL3788743 0.61 ADORA2B (0.38) LMNAADORA2BKDM4EALDH1A1GLA
SCHEMBL73817 0.60 PDE4A (0.35) CYP2C9LMNAADORA2BKDM4EALDH1A1
SCHEMBL25086826 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021139482-A1 CARBOXYLIC ACID DERIVATIVE-SUBSTITUTED IMINO ARYL COMPOUND, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF 青岛清原化合物有限公司 2021-07-15 WO disclosed