SCHEMBL23635607

SCHEMBL23635607

Cn1c(C(F)(F)F)c(Cl)c(=O)n(C)c1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 5/20 0.37
ALDH1A1 P00352 5/20 0.37
KDM4E B2RXH2 4/20 0.37
LMNA P02545 2/20 0.37
HPGD P15428 2/20 0.37
JAK2 O60674 1/20 0.37
PAX8 Q06710 1/20 0.37
ADORA2A P29274 2/20 0.34
ITGB1 P05556 2/20 0.34
ITGA4 P13612 2/20 0.34
ITGB7 P26010 2/20 0.34
NPC1 O15118 1/20 0.33
S1PR2 O95136 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
GLP1R P43220 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25086826 0.81
SCHEMBL23635717 0.75 ADORA2A (0.31) HTTLMNAADORA2ANPC1S1PR2
SCHEMBL23635681 0.72 AOC3 (0.34) ALDH1A1KDM4EHPGDADORA2ACYP1A2
SCHEMBL23635682 0.72 CYP2C9 (0.39) ALDH1A1KDM4ELMNAADORA2AITGB1
SCHEMBL7939182 0.71 ALDH1A1 (0.40) HTTALDH1A1KDM4ELMNAHPGD
SCHEMBL9769938 0.70 ALDH1A1 (0.42) HTTALDH1A1KDM4ELMNAHPGD
SCHEMBL25979903 0.69 ALDH1A1 (0.48) HTTALDH1A1KDM4ELMNAHPGD
SCHEMBL7532405 0.67 ALDH1A1 (0.40) HTTALDH1A1KDM4ELMNAHPGD
SCHEMBL25980036 0.67 ALDH1A1 (0.48) HTTALDH1A1KDM4ELMNAHPGD
SCHEMBL13575169 0.64 ALDH1A1 (0.38) HTTALDH1A1KDM4ELMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021143677-A1 FUSED RING SUBSTITUTED AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION, AND USE THEREOF 青岛清原化合物有限公司 2021-07-22 WO disclosed
WO-2021139482-A1 CARBOXYLIC ACID DERIVATIVE-SUBSTITUTED IMINO ARYL COMPOUND, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF 青岛清原化合物有限公司 2021-07-15 WO disclosed