SCHEMBL23635987

SCHEMBL23635987

COCc1ccc(OC)cc1-c1nnc(NS(=O)(=O)c2c(OC)cccc2OC)s1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
ALDH1A1 P00352 11/20 0.43
HPGD P15428 3/20 0.43
NPC1 O15118 2/20 0.43
NPSR1 Q6W5P4 2/20 0.42
KDM4E B2RXH2 2/20 0.42
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PKM P14618 2/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA5A P35218 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
GGT1 P19440 1/20 0.40
AMY1A P0DUB6 1/20 0.40
POLB P06746 1/20 0.40
CTDSP1 Q9GZU7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23292605 0.87 KMT2A (0.48) RXFP1MEN1KMT2AALDH1A1HPGD
SCHEMBL23635977 0.84 RXFP1 (0.46) RXFP1MEN1KMT2AALDH1A1HPGD
SCHEMBL23292521 0.80 KAT7 (0.41) MEN1KMT2AALDH1A1HPGDNPSR1
SCHEMBL27097756 0.79 KDM4E (0.59) MEN1KMT2AALDH1A1HPGDNPC1
SCHEMBL23635965 0.78 KDM4E (0.52) MEN1KMT2AALDH1A1HPGDNPC1
SCHEMBL23635980 0.78 AMY1A (0.50) MEN1KMT2AALDH1A1HPGDNPC1
SCHEMBL23292567 0.75 NPC1 (0.54) RXFP1MEN1KMT2AALDH1A1HPGD
SCHEMBL23635961 0.73 KDM4E (0.44) MEN1KMT2AALDH1A1HPGDNPC1
SCHEMBL23635973 0.73 SCN9A (0.45) MEN1KMT2AALDH1A1HPGDNPC1
SCHEMBL23292540 0.71 KDM4E (0.54) ALDH1A1HPGDNPC1KDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11911372-B2 Compounds CTXT PTY LTD (AU) 2024-02-27 US disclosed
US-11911372-B2 Compounds CTXT PTY LTD (AU) 2024-02-27 US disclosed
US-20210213004-A1 Compounds CTXT PTY LTD (AU) 2021-07-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210213004-A1 Compounds SLC10A1, ABCB11, REN RXFP1 1430/4885MEN1 114/4885KMT2A 4080/4885
US-11911372-B2 Compounds SLC10A1, ABCB11, REN RXFP1 1430/4885MEN1 114/4885KMT2A 4080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.