Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.48 |
| ▸ | RORC | P51449 | 12/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28600987 | 1.00 | MCHR1 (0.48) | MCHR1RORCHDAC8HDAC6 | |
| SCHEMBL30065059 | 1.00 | MCHR1 (0.48) | MCHR1RORCHDAC8HDAC6 | |
| SCHEMBL23637002 | 0.87 | RORC (0.47) | RORC | |
| SCHEMBL23636633 | 0.87 | RORC (0.47) | RORC | |
| SCHEMBL23636937 | 0.85 | RORC (0.45) | RORC | |
| SCHEMBL21619696 | 0.85 | RORC (0.51) | RORC | |
| SCHEMBL23632651 | 0.84 | ACACB (0.53) | — | |
| SCHEMBL23632744 | 0.84 | ACACB (0.53) | — | |
| SCHEMBL23632653 | 0.84 | ACACB (0.53) | — | |
| SCHEMBL23632785 | 0.84 | ACACB (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072476-B | ROR gamma t inhibitor and preparation method and application thereof | 广东东阳光药业股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| WO-2021139599-A1 | RORγT INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 东莞市东阳光新药研发有限公司 | 2021-07-15 | — | — | WO | disclosed |
| CN-113072476-A | ROR gamma t inhibitor and preparation method and application thereof | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | disclosed |