Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.48 |
| ▸ | RORC | P51449 | 12/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28600987 | 1.00 | MCHR1 (0.48) | MCHR1RORCHDAC8HDAC6 | |
| SCHEMBL23636960 | 1.00 | MCHR1 (0.48) | MCHR1RORCHDAC8HDAC6 | |
| SCHEMBL23637002 | 0.87 | RORC (0.47) | RORC | |
| SCHEMBL23636633 | 0.87 | RORC (0.47) | RORC | |
| SCHEMBL23636937 | 0.85 | RORC (0.45) | RORC | |
| SCHEMBL21619696 | 0.85 | RORC (0.51) | RORC | |
| SCHEMBL23632651 | 0.84 | ACACB (0.53) | — | |
| SCHEMBL23632744 | 0.84 | ACACB (0.53) | — | |
| SCHEMBL23632653 | 0.84 | ACACB (0.53) | — | |
| SCHEMBL23632785 | 0.84 | ACACB (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4089079-A1 | ROR GAMMA T INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2022-11-16 | — | — | EP | disclosed |