Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 18/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21619697 | 0.96 | RORC (0.50) | RORCPDE2A | |
| SCHEMBL23636942 | 0.92 | HDAC1 (0.60) | RORCHDAC1 | |
| SCHEMBL21619715 | 0.86 | RORC (0.47) | RORC | |
| SCHEMBL21619742 | 0.85 | RORC (0.43) | RORC | |
| SCHEMBL21619695 | 0.85 | RORC (0.45) | RORC | |
| SCHEMBL30065059 | 0.85 | MCHR1 (0.48) | RORC | |
| SCHEMBL28600987 | 0.85 | MCHR1 (0.48) | RORC | |
| SCHEMBL23636960 | 0.85 | MCHR1 (0.48) | RORC | |
| SCHEMBL21619714 | 0.83 | RORC (0.43) | RORC | |
| SCHEMBL23619004 | 0.83 | RORC (0.49) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020011147-A1 | RORγ ANTAGONIST AND APPLICATION THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-01-16 | — | — | WO | disclosed |