Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30714973 | 0.74 | PIK3C3 (0.41) | — | |
| SCHEMBL29138859 | 0.73 | CYP1A2 (0.33) | — | |
| SCHEMBL23213435 | 0.71 | PIK3C3 (0.41) | PDE4DATR | |
| SCHEMBL29651014 | 0.70 | — | — | |
| SCHEMBL29138900 | 0.69 | HIF1A (0.39) | — | |
| SCHEMBL29138869 | 0.69 | HIF1A (0.39) | — | |
| SCHEMBL17076741 | 0.69 | PIK3C3 (0.33) | — | |
| SCHEMBL29138887 | 0.68 | SMN1; SMN2 (0.38) | ATR | |
| SCHEMBL29138874 | 0.68 | SMN1; SMN2 (0.38) | ATR | |
| SCHEMBL29138795 | 0.68 | ATM (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350077-A1 | FUSED, SPIROCYCLIC HETEROAROMATIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | AstraZeneca AB (SE) | 2011-08-03 | — | — | EP | disclosed |