Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.31 |
| ▸ | MTOR | P42345 | 2/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.30 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138869 | 0.81 | HIF1A (0.39) | PIK3CAMTORHDAC6HDAC8 | |
| SCHEMBL29138900 | 0.81 | HIF1A (0.39) | PIK3CAMTORHDAC6HDAC8 | |
| SCHEMBL29138907 | 0.81 | HRH3 (0.37) | HDAC6HDAC8HDAC1KCNH2 | |
| SCHEMBL29651014 | 0.80 | — | — | |
| SCHEMBL29138797 | 0.77 | PIK3CD (0.30) | PIK3CAMTOR | |
| SCHEMBL29138880 | 0.75 | HDAC4 (0.36) | PIK3CAMTORHDAC6HDAC8HDAC1 | |
| SCHEMBL29138881 | 0.75 | HDAC4 (0.36) | PIK3CAMTORHDAC6HDAC8HDAC1 | |
| SCHEMBL29138918 | 0.73 | AKR1C3 (0.39) | HDAC6HDAC8HDAC1 | |
| SCHEMBL29138870 | 0.73 | AKR1C3 (0.39) | HDAC6HDAC8HDAC1 | |
| SCHEMBL29138796 | 0.73 | AKR1C3 (0.39) | HDAC6HDAC8HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888120-A | PRMTS inhibitors | 美国安进公司 | 2023-10-13 | — | — | CN | claimed |
| CN-116888120-A | PRMTS inhibitors | 美国安进公司 | 2023-10-13 | — | — | CN | disclosed |