SCHEMBL30714973

SCHEMBL30714973

O=CN1CCOCC1c1ccccn1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PIK3C3 Q8NEB9 2/20 0.41
RIPK1 Q13546 1/20 0.36
MTOR P42345 3/20 0.35
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 2/20 0.35
HSD17B10 Q99714 2/20 0.35
HPGD P15428 1/20 0.35
PRMT5 O14744 1/20 0.35
WDR77 Q9BQA1 1/20 0.35
MAPT P10636 2/20 0.35
AR P10275 1/20 0.35
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPC1 O15118 1/20 0.34
KMT2A Q03164 1/20 0.34
NPEPPS P55786 1/20 0.34
NUDT1 P36639 1/20 0.34
PDE10A Q9Y233 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29138859 0.82 CYP1A2 (0.33) ALDH1A1KDM4EHSD17B10HPGDNUDT1
SCHEMBL16795107 0.78 PIK3C3 (0.43) PIK3C3RIPK1MTORALDH1A1MAPT
SCHEMBL4153660 0.78 ALDH1A1 (0.43) PIK3C3RIPK1ALDH1A1KDM4EPRMT5
SCHEMBL18153252 0.77 PIK3C3 (0.45) PIK3C3RIPK1MTORALDH1A1MAPT
SCHEMBL29933840 0.76 PIK3C3 (0.41) PIK3C3RIPK1ALDH1A1KDM4EHSD17B10
SCHEMBL976308 0.75 PIK3C3 (0.47) PIK3C3MTORALDH1A1MAPTNPEPPS
SCHEMBL29138869 0.75 HIF1A (0.39) MTORKDM4EMAPTSMN1; SMN2
SCHEMBL29138900 0.75 HIF1A (0.39) MTORKDM4EMAPTSMN1; SMN2
SCHEMBL5164090 0.74 PLD1 (0.40) RIPK1ALDH1A1MAPTRAB9ANPC1
SCHEMBL2363701 0.74 PDE4D (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114867529-B Novel heteroaryl triazole compounds as pesticides 拜耳公司 2024-09-27 CN disclosed
CN-117567338-A Novel heteroaryl triazole compounds as pesticides 拜耳公司 2024-02-20 CN disclosed