Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138869 | 1.00 | HIF1A (0.39) | HIF1AEPAS1TMEM97SIGMAR1LIPE | |
| SCHEMBL29138795 | 0.81 | ATM (0.31) | HDAC8HDAC6PIK3CAMTOR | |
| SCHEMBL29138918 | 0.80 | AKR1C3 (0.39) | HIF1AEPAS1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL29138870 | 0.80 | AKR1C3 (0.39) | HIF1AEPAS1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL29138796 | 0.80 | AKR1C3 (0.39) | HIF1AEPAS1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL31424110 | 0.78 | KDM4E (0.34) | HIF1AEPAS1TMEM97SIGMAR1LIPE | |
| SCHEMBL29138856 | 0.77 | HCRTR1 (0.33) | LMNASMN1; SMN2PIK3CAMTOR | |
| SCHEMBL29138906 | 0.77 | KDM4E (0.32) | HIF1AEPAS1FGFR4KDM4EABL1 | |
| SCHEMBL29138939 | 0.75 | LMNA (0.36) | KDM4ELMNASMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL30714973 | 0.75 | PIK3C3 (0.41) | KDM4EMAPTSMN1; SMN2MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888120-A | PRMTS inhibitors | 美国安进公司 | 2023-10-13 | — | — | CN | disclosed |