SCHEMBL23637357

SCHEMBL23637357

Fc1ccc2oc3cc(C4(c5ccccc5)c5ccccc5-c5ccccc54)cc(Cl)c3c2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.39
WEE1 P30291 2/20 0.35
TNKS O95271 1/20 0.35
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
OPRK1 P41145 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GABRP O00591 2/20 0.32
GABRD O14764 2/20 0.32
GABRA1 P14867 2/20 0.32
GABRB1 P18505 2/20 0.32
GABRG2 P18507 2/20 0.32
GABRB3 P28472 2/20 0.32
GABRA5 P31644 2/20 0.32
GABRA3 P34903 2/20 0.32
GABRA2 P47869 2/20 0.32
GABRB2 P47870 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23637442 0.86 AHR (0.40) AHRWEE1KDM4EMEN1LMNA
SCHEMBL23637361 0.75 PDK2 (0.37) AHRWEE1TNKSKDM4EMEN1
SCHEMBL20218923 0.74 MEN1 (0.39) AHRWEE1KDM4EMEN1LMNA
SCHEMBL23637433 0.73 TNKS (0.38) AHRWEE1TNKSKDM4EMEN1
SCHEMBL26574532 0.73 AHR (0.35) AHRWEE1TNKSKDM4EMEN1
SCHEMBL24287085 0.73 ALOX5 (0.41) TNKSKDM4EMEN1LMNAMAPT
SCHEMBL23098749 0.73 AHR (0.46) AHRWEE1TNKSGABRPGABRD
SCHEMBL23637485 0.73 AHR (0.46) AHRKDM4EMEN1LMNAMAPT
SCHEMBL22698482 0.72 PIM1 (0.33) AHRWEE1KDM4EMEN1LMNA
SCHEMBL23098697 0.72 AHR (0.48) AHRTNKSKDM4EMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021141356-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-07-15 WO disclosed