SCHEMBL23637785

SCHEMBL23637785

O=Cc1ccc(C(=C(c2ccc(C=O)cc2)c2ccc(C=O)cc2)c2ccc(C=O)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.64
ALDH5A1 P51649 1/20 0.57
ABAT P80404 1/20 0.57
CYP2A6 P11509 4/20 0.50
KDM4E B2RXH2 2/20 0.50
HSD17B10 Q99714 1/20 0.50
PARP10 Q53GL7 1/20 0.48
PARP3 Q9Y6F1 1/20 0.48
EGFR P00533 2/20 0.44
TYR P14679 1/20 0.44
PTGS2 P35354 1/20 0.44
RAB9A P51151 1/20 0.44
CYP2A13 Q16696 1/20 0.44
ALDH1A3 P47895 2/20 0.41
ALDH3A1 P30838 1/20 0.41
KCNJ1 P48048 1/20 0.40
TRIM24 O15164 1/20 0.39
TRIM33 Q9UPN9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30516987 0.92 ALDH1A1 (0.56) ALDH1A1ALDH5A1ABATCYP2A6KDM4E
SCHEMBL31674561 0.90 ALDH1A1 (0.60) ALDH1A1ALDH5A1ABATCYP2A6KDM4E
SCHEMBL15901558 0.90 ALDH1A1 (0.60) ALDH1A1ALDH5A1ABATCYP2A6KDM4E
SCHEMBL15906941 0.84 ALDH1A1 (0.54) ALDH1A1ALDH5A1ABATCYP2A6RAB9A
SCHEMBL29244371 0.82 ALDH1A1 (0.52) ALDH1A1ALDH5A1ABATCYP2A6RAB9A
SCHEMBL30510210 0.82 ALDH5A1 (0.64) ALDH1A1ALDH5A1ABATCYP2A6RAB9A
SCHEMBL29244592 0.82 ALDH1A1 (0.52) ALDH1A1ALDH5A1ABATCYP2A6RAB9A
SCHEMBL4956384 0.80 CYP2A6 (0.69) ALDH1A1ALDH5A1ABATCYP2A6KDM4E
SCHEMBL31171 0.80 CYP2A6 (0.69) ALDH1A1ALDH5A1ABATCYP2A6KDM4E
SCHEMBL3757660 0.80 ALDH1A1 (0.68) ALDH1A1ALDH5A1ABATCYP2A6KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117717902-A Preparation method and application of covalent organic framework nanofiltration membrane 天津大学 2024-03-19 CN claimed
CN-117384333-A Covalent organic framework material based on benzodifurandione, preparation method and application thereof 中国科学院兰州化学物理研究所 2024-01-12 CN claimed
CN-114085388-B Covalent organic framework material containing oxadiazole connecting element 河北工业大学 2022-12-16 CN claimed
CN-114085388-A Covalent organic framework material containing oxadiazole connecting element 河北工业大学 2022-02-25 CN claimed
US-12391800-B1 Tetraphenylethene-based polymers for supercapacitors IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2025-08-19 US disclosed
WO-2025007645-A1 METHOD FOR DETECTING HEXAMETHYLENEDIAMINE 岭南师范学院 2025-01-09 WO disclosed
CN-116973343-B Method for detecting hexamethylenediamine 岭南师范学院 2024-07-16 CN disclosed
CN-117717902-A Preparation method and application of covalent organic framework nanofiltration membrane 天津大学 2024-03-19 CN disclosed
CN-117384333-A Covalent organic framework material based on benzodifurandione, preparation method and application thereof 中国科学院兰州化学物理研究所 2024-01-12 CN disclosed
CN-116093283-A Phthalocyanine-based covalent organic framework coated nano silicon composite material and preparation method thereof 宜春江理锂电新能源产业研究院 2023-05-09 CN disclosed
CN-115505102-A Preparation of two-dimensional covalent organic framework yellow light material capable of being excited by blue light for LEDs 云南民族大学 2022-12-23 CN disclosed
CN-114085388-B Covalent organic framework material containing oxadiazole connecting element 河北工业大学 2022-12-16 CN disclosed
CN-113354588-B Chiral luminescent metal-organic cage complex and preparation method and application thereof 国家纳米科学中心 2022-05-31 CN disclosed
CN-113354588-A Chiral luminescent metal-organic cage complex and preparation method and application thereof 国家纳米科学中心 2021-09-07 CN disclosed
CN-112156758-B Porous material and preparation method and application thereof 清华大学 2021-08-31 CN disclosed
WO-2021142474-A1 COVALENT ORGANIC FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-07-15 WO disclosed
CN-112156758-A Porous material and preparation method and application thereof 清华大学 2021-01-01 CN disclosed