SCHEMBL3757660

SCHEMBL3757660

O=Cc1ccc(C(=O)C(=O)c2ccc(C=O)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.68
ALDH5A1 P51649 1/20 0.55
ABAT P80404 1/20 0.55
PARP10 Q53GL7 1/20 0.52
PARP3 Q9Y6F1 1/20 0.52
CES2 O00748 8/20 0.50
CES1 P23141 8/20 0.50
KDM4E B2RXH2 1/20 0.48
CYP2A6 P11509 2/20 0.48
HSD17B10 Q99714 1/20 0.48
EGFR P00533 1/20 0.43
TYR P14679 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30337112 0.93 ALDH1A1 (0.60) ALDH1A1ALDH5A1ABATPARP10PARP3
SCHEMBL28271046 0.91 CES2 (0.68) ALDH1A1ALDH5A1ABATPARP10PARP3
SCHEMBL6852409 0.83 ALDH1A1 (0.68) ALDH1A1ALDH5A1ABATPARP10PARP3
Benzil SCHEMBL7790900 0.82 CES2 (0.67) ALDH1A1CES2CES1CYP2A6
SCHEMBL12344141 0.82 ALDH1A1 (0.54) ALDH1A1ALDH5A1ABATPARP10PARP3
Terephthalic Acid SCHEMBL11068404 0.81 ALDH1A1 (1.00) ALDH1A1ALDH5A1ABATPARP10PARP3
SCHEMBL1664743 0.81 ALDH1A1 (0.65) ALDH1A1ALDH5A1ABATPARP10PARP3
SCHEMBL18133156 0.81 ALDH1A1 (0.65) ALDH1A1ALDH5A1ABATPARP10PARP3
SCHEMBL63361 0.81 ALDH1A1 (1.00) ALDH1A1ALDH5A1ABATPARP10PARP3
SCHEMBL28435221 0.80 ALDH1A1 (0.66) ALDH1A1ALDH5A1ABATPARP10PARP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7842830-B2 Transition-metal charge-transport materials, methods of fabrication thereof, and methods of use thereof GEORGIA TECH RESEARCH CORPORATION (US) 2010-11-30 US disclosed
US-20080121870-A1 Transition-Metal Charge Transport Materials, Methods Of Fabrication Thereof, And Methods Of Use Thereof GEORGIA TECH RESEACH CORPORATION 2008-05-29 US disclosed
WO-2005123754-A2 TRANSITION-METAL CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF GEORGIA TECH RESEARCH CORPORATION (US) 2005-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080121870-A1 Transition-Metal Charge Transport Materials, Methods Of Fabrication Thereof, And Methods Of Use Thereof SLC39A3, SLC6A6, SLC6A9 ALDH1A1 2421/4885ALDH5A1 2201/4885ABAT 818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.