Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 8/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23638468 | 0.84 | IRAK4 (0.39) | IRAK4LPLLIPGIDO1TDO2 | |
| SCHEMBL17673811 | 0.82 | SNCA (0.38) | IRAK4LPLLIPGIDO1TDO2 | |
| SCHEMBL17678259 | 0.82 | IRAK4 (0.38) | IRAK4LPLLIPGIDO1TDO2 | |
| SCHEMBL23638264 | 0.82 | IRAK4 (0.40) | ESR2IRAK4LPLLIPGIDO1 | |
| SCHEMBL17678253 | 0.81 | LMNA (0.48) | MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23638463 | 0.80 | IRAK4 (0.39) | ESR2IRAK4LPLLIPGIDO1 | |
| SCHEMBL29837912 | 0.80 | L3MBTL1 (0.40) | IRAK4LPLLIPGIDO1TDO2 | |
| SCHEMBL28807179 | 0.80 | L3MBTL1 (0.40) | IRAK4LPLLIPGIDO1TDO2 | |
| SCHEMBL23638435 | 0.80 | ALDH1A1 (0.36) | IRAK4LPLLIPGIDO1TDO2 | |
| SCHEMBL17678254 | 0.79 | KDM4E (0.48) | IRAK4MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901664-B | Pyridone compounds and uses thereof | 南京再明医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-114901664-A | Pyridone compound and application thereof | 江苏先声药业有限公司 | 2022-08-12 | — | — | CN | disclosed |
| WO-2021139775-A1 | PYRIDONE COMPOUND AND APPLICATION | 江苏先声药业有限公司 | 2021-07-15 | — | — | WO | disclosed |