Dibenzoylmethane

Dibenzoylmethane

SCHEMBL2363871

Brc1cc2cccnc2c2ncccc12.O=C(CC(=O)c1ccccc1)c1ccccc1.O=C(CC(=O)c1ccccc1)c1ccccc1.O=C(CC(=O)c1ccccc1)c1ccccc1.[Eu]

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.46
KDR P35968 1/20 0.45
KDM4E B2RXH2 4/20 0.44
KMT2A Q03164 4/20 0.44
MEN1 O00255 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
PLOD2 O00469 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
TP53 P04637 2/20 0.44
USP2 O75604 1/20 0.44
HSP90AA1 P07900 1/20 0.44
HTT P42858 1/20 0.44
ALDH1A1 P00352 3/20 0.44
CYP3A4 P08684 2/20 0.44
HPGD P15428 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
PLOD3 O60568 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibenzoylmethane SCHEMBL28803142 0.85 CYP3A4 (0.57) KDRKDM4EKMT2AMEN1SMN1; SMN2
Dibenzoylmethane SCHEMBL3478420 0.85 CYP3A4 (0.57) KDRKDM4EKMT2AMEN1SMN1; SMN2
Dibenzoylmethane SCHEMBL22092884 0.85 ADORA3 (0.46) ADORA3KDRKDM4EKMT2AMEN1
Dibenzoylmethane SCHEMBL3478408 0.85 ADORA3 (0.46) ADORA3KDRKDM4EKMT2AMEN1
Dibenzoylmethane SCHEMBL28036057 0.83 CYP3A4 (0.59) KDRKDM4EKMT2AMEN1SMN1; SMN2
Dibenzoylmethane SCHEMBL17022453 0.83 CYP3A4 (0.59) KDRKDM4EKMT2AMEN1SMN1; SMN2
SCHEMBL504434 0.80 CCR1 (0.61) KDM4EKMT2AMEN1SMN1; SMN2TDP1
Dibenzoylmethane SCHEMBL1969521 0.79 LMNA (0.62) ADORA3KDRKDM4EKMT2AMEN1
Dibenzoylmethane SCHEMBL27683419 0.79 LMNA (0.62) ADORA3KDRKDM4EKMT2AMEN1
Dibenzoylmethane SCHEMBL22734490 0.79 ADORA3 (0.41) ADORA3KDRKDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10141513-B2 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-11-27 US disclosed
US-20140183508-A1 POLYMERIC LIGHT EMITTING SUBSTANCE AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-03 US disclosed
US-20110187969-A1 POLYMERIC LIGHT EMITTING SUBSTANCE AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-04 US disclosed