Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | LGMN | Q99538 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29744988 | 0.84 | LGMN (0.51) | ALDH1A1LGMNLMNAKDM4EMAPT | |
| SCHEMBL2311204 | 0.84 | LGMN (0.51) | ALDH1A1LGMNLMNAKDM4EMAPT | |
| SCHEMBL24196340 | 0.83 | ALDH1A1 (0.50) | ALDH1A1LGMNLMNAKDM4EMAPT | |
| SCHEMBL518889 | 0.80 | ALDH1A1 (0.50) | ALDH1A1LGMNLMNAKDM4EMAPT | |
| SCHEMBL21262291 | 0.79 | MAPT (0.54) | ALDH1A1LGMNLMNAKDM4EMAPT | |
| SCHEMBL3922530 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LGMNLMNAKDM4EMAPT | |
| SCHEMBL10994974 | 0.79 | ALDH1A1 (0.47) | ALDH1A1LGMNLMNAKDM4EMAPT | |
| SCHEMBL2314955 | 0.78 | ALDH1A1 (0.57) | ALDH1A1LGMNLMNAKDM4EMAPT | |
| SCHEMBL29300840 | 0.75 | ALDH1A1 (0.47) | ALDH1A1LGMNLMNAKDM4EMAPT | |
| SCHEMBL23759790 | 0.75 | ALDH1A1 (0.61) | ALDH1A1LGMNLMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888579-B1 | NOVEL FLUORENE DERIVATIVES, COMPOSITION CONTAINING SAID DERIVATIVES AND THE USE THEREOF | AVENTIS PHARMA SA (FR) | 2011-08-03 | — | — | EP | disclosed |
| EP-1888579-A2 | NOVEL FLUORENE DERIVATIVES, COMPOSITION CONTAINING SAID DERIVATIVES AND THE USE THEREOF | Aventis Pharma S.A. (FR) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006123061-A2 | FLUORENE DERIVATIVES, COMPOSITION CONTAINING SAID DERIVATIVES AND THE USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2006-11-23 | — | — | WO | disclosed |