Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | LGMN | Q99538 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL518889 | 0.93 | ALDH1A1 (0.50) | ALDH1A1LGMNKDM4ELMNAMAPT | |
| SCHEMBL2311204 | 0.91 | LGMN (0.51) | ALDH1A1LGMNKDM4ELMNAMAPT | |
| SCHEMBL29744988 | 0.91 | LGMN (0.51) | ALDH1A1LGMNKDM4ELMNAMAPT | |
| SCHEMBL3922530 | 0.84 | ALDH1A1 (0.50) | ALDH1A1LGMNKDM4ELMNAMAPT | |
| SCHEMBL21262291 | 0.84 | MAPT (0.54) | ALDH1A1LGMNKDM4ELMNAMAPT | |
| SCHEMBL10994974 | 0.84 | ALDH1A1 (0.47) | ALDH1A1LGMNKDM4ELMNAMAPT | |
| SCHEMBL24196353 | 0.84 | ALDH1A1 (0.50) | ALDH1A1LGMNKDM4ELMNAMAPT | |
| SCHEMBL24196251 | 0.84 | LGMN (0.46) | ALDH1A1LGMNKDM4ELMNAMAPT | |
| SCHEMBL2363906 | 0.83 | ALDH1A1 (0.46) | ALDH1A1LGMNKDM4ELMNAMAPT | |
| SCHEMBL23759790 | 0.81 | ALDH1A1 (0.61) | ALDH1A1LGMNKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022011274-A1 | SUBSTITUTED 1,6-NAPHTHYRIDINE INHIBITORS OF CDK5 | GOLDFINCH BIO, INC. (US) | 2022-01-13 | — | — | WO | disclosed |