SCHEMBL23639909

SCHEMBL23639909

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nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.42
TRPM8 Q7Z2W7 2/20 0.42
GBA1 P04062 5/20 0.33
SI P14410 1/20 0.30
PYGL P06737 1/20 0.30
GBA2 Q9HCG7 1/20 0.30
GAA P10253 1/20 0.30
GLB1 P16278 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23691616 0.80 TRPA1 (0.33) TRPA1TRPM8
SCHEMBL6909669 0.80 GBA1 (0.33) TRPA1TRPM8GBA1SIPYGL
SCHEMBL11960304 0.79
SCHEMBL12986353 0.79
SCHEMBL13747920 0.79
SCHEMBL12985849 0.79
SCHEMBL11960305 0.79
SCHEMBL10093807 0.76 SI (0.45) TRPA1TRPM8GBA1SIPYGL
SCHEMBL22179332 0.76 SI (0.45) TRPA1TRPM8GBA1SIPYGL
SCHEMBL22174658 0.76 SI (0.45) TRPA1TRPM8GBA1SIPYGL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214607-A1 LONG WAVELENGTH EMITTING CHEMILUMINESCENT PROBES NEMIS TECHNOLOGIES AG (CH) 2021-07-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210214607-A1 LONG WAVELENGTH EMITTING CHEMILUMINESCENT PROBES VEGFA, GUSB, NR2E3 TRPA1 2717/4885TRPM8 2584/4885GBA1 2823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.