Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BDNF | P23560 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PTN | P21246 | 2/20 | 0.40 |
| ▸ | MDK | P21741 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CD69 | Q07108 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17689074 | 0.85 | MAPK1 (0.45) | ALDH1A1THRBBDNFMAPK1PTN | |
| SCHEMBL30089326 | 0.85 | MAPK1 (0.45) | ALDH1A1THRBBDNFMAPK1PTN | |
| SCHEMBL15965653 | 0.85 | MAPK1 (0.45) | ALDH1A1THRBBDNFMAPK1PTN | |
| SCHEMBL23631128 | 0.85 | MAPK1 (0.45) | ALDH1A1THRBBDNFMAPK1PTN | |
| SCHEMBL15966272 | 0.85 | MAPK1 (0.45) | ALDH1A1THRBBDNFMAPK1PTN | |
| SCHEMBL22362645 | 0.85 | MAPK1 (0.45) | ALDH1A1THRBBDNFMAPK1PTN | |
| SCHEMBL15966248 | 0.85 | MAPK1 (0.45) | ALDH1A1THRBBDNFMAPK1PTN | |
| SCHEMBL20474503 | 0.85 | MAPK1 (0.45) | ALDH1A1THRBBDNFMAPK1PTN | |
| SCHEMBL16566075 | 0.84 | ALDH1A1 (0.40) | ALDH1A1THRBBDNFMAPK1PTN | |
| SCHEMBL16998721 | 0.84 | ALDH1A1 (0.55) | ALDH1A1THRBBDNFMAPK1PTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203082-A1 | REAGENTS AND METHODS FOR SCREENING MPS I, II, IIIA, IIIB, IVA, VI, AND VII | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2023-06-29 | — | — | US | disclosed |
| US-20210214607-A1 | LONG WAVELENGTH EMITTING CHEMILUMINESCENT PROBES | NEMIS TECHNOLOGIES AG (CH) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203082-A1 | REAGENTS AND METHODS FOR SCREENING MPS I, II, IIIA, IIIB, IVA, VI, AND VII | GAA, MAN2B1, CLN6 | ALDH1A1 1851/4885THRB 2967/4885BDNF 4504/4885 |
| US-20210214607-A1 | LONG WAVELENGTH EMITTING CHEMILUMINESCENT PROBES | VEGFA, GUSB, NR2E3 | ALDH1A1 297/4885THRB 2211/4885BDNF 4009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.