SCHEMBL30089326

SCHEMBL30089326

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nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 2/20 0.45
▸ AMDHD2 Q9Y303 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.40
▸ THRB P10828 1/20 0.40
▸ LMNA P02545 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ CYP2D6 P10635 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ PTN P21246 1/20 0.40
▸ MDK P21741 1/20 0.40
▸ BDNF P23560 1/20 0.40
▸ CA1 P00915 1/20 0.37
▸ CA2 P00918 1/20 0.37
▸ CA9 Q16790 1/20 0.37
▸ CD69 Q07108 1/20 0.37
▸ HK1 P19367 1/20 0.37
▸ HK2 P52789 1/20 0.37
▸ LGALS3 P17931 1/20 0.36
▸ F10 P00742 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17689074 1.00 MAPK1 (0.45) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL22362645 1.00 MAPK1 (0.45) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL15966272 1.00 MAPK1 (0.45) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL20474503 1.00 MAPK1 (0.45) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL15966248 1.00 MAPK1 (0.45) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL23631128 1.00 MAPK1 (0.45) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL15965653 1.00 MAPK1 (0.45) MAPK1AMDHD2ALDH1A1THRBLMNA
Phosphoric Acid SCHEMBL27756060 0.95 AMDHD2 (0.46) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL20415021 0.88 BDNF (0.38) MAPK1ALDH1A1THRBPTNMDK
SCHEMBL16566075 0.87 ALDH1A1 (0.40) MAPK1ALDH1A1THRBPTNMDK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4401753-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER AND ENHANCING IMMUNE CHECKPOINT INHIBITOR EFFICACY Gnubiotics Sciences SA (CH) 2024-07-24 — — EP claimed
WO-2023041979-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER AND ENHANCING IMMUNE CHECKPOINT INHIBITOR EFFICACY GNUBIOTICS SCIENCES SA (CH) 2023-03-23 — — WO claimed
WO-2023037165-A1 METHODS AND COMPOSITIONS FOR REDUCING NEUTROPHILS OR NEUTROPHIL INFILTRATION AT THE SITE OF DISEASE GNUBIOTICS SCIENCES SA (CH) 2023-03-16 — — WO claimed
US-12630593-B2 Method of killing leukemia cells by administration of recombinant'Y3 proteins UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2026-05-19 — — US disclosed
US-20240382560-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER AND ENHANCING IMMUNE CHECKPOINT INHIBITOR EFFICACY GNUBIOTICS SCIENCES SA (CH) 2024-11-21 — — US disclosed
EP-4401753-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER AND ENHANCING IMMUNE CHECKPOINT INHIBITOR EFFICACY Gnubiotics Sciences SA (CH) 2024-07-24 — — EP disclosed
US-20230272019-A1 FUNGAL GLYCAN BINDING PROTEIN WHICH POSSESSES ANTIVIRAL AND ANTICANCER ACTIVITY UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2023-08-31 — — US disclosed
WO-2023041979-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER AND ENHANCING IMMUNE CHECKPOINT INHIBITOR EFFICACY GNUBIOTICS SCIENCES SA (CH) 2023-03-23 — — WO disclosed
WO-2023037165-A1 METHODS AND COMPOSITIONS FOR REDUCING NEUTROPHILS OR NEUTROPHIL INFILTRATION AT THE SITE OF DISEASE GNUBIOTICS SCIENCES SA (CH) 2023-03-16 — — WO disclosed
US-11512119-B2 Fungal glycan binding protein which possesses antiviral and anticancer activity UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2022-11-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630593-B2 Method of killing leukemia cells by administration of recombinant'Y3 proteins L3MBTL3, CHI3L1, BCL3 MAPK1 1568/4885AMDHD2 3196/4885ALDH1A1 4731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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