SCHEMBL20474503

SCHEMBL20474503

CC(=O)N[C@H]1C(O)O[C@H](COS(=O)(=O)O)[C@H](O)[C@@H]1O

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 2/20 0.45
▸ AMDHD2 Q9Y303 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.40
▸ THRB P10828 1/20 0.40
▸ LMNA P02545 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ CYP2D6 P10635 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ PTN P21246 1/20 0.40
▸ MDK P21741 1/20 0.40
▸ BDNF P23560 1/20 0.40
▸ CA1 P00915 1/20 0.37
▸ CA2 P00918 1/20 0.37
▸ CA9 Q16790 1/20 0.37
▸ CD69 Q07108 1/20 0.37
▸ HK1 P19367 1/20 0.37
▸ HK2 P52789 1/20 0.37
▸ LGALS3 P17931 1/20 0.36
▸ F10 P00742 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17689074 1.00 MAPK1 (0.45) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL22362645 1.00 MAPK1 (0.45) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL15966272 1.00 MAPK1 (0.45) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL30089326 1.00 MAPK1 (0.45) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL15966248 1.00 MAPK1 (0.45) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL23631128 1.00 MAPK1 (0.45) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL15965653 1.00 MAPK1 (0.45) MAPK1AMDHD2ALDH1A1THRBLMNA
Phosphoric Acid SCHEMBL27756060 0.95 AMDHD2 (0.46) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL20415021 0.88 BDNF (0.38) MAPK1ALDH1A1THRBPTNMDK
SCHEMBL16566075 0.87 ALDH1A1 (0.40) MAPK1ALDH1A1THRBPTNMDK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119375384-A Method for in-vitro detection of mucopolysaccharide and pompe disease related biomarker 浙江博圣生物技术股份有限公司 2025-01-28 — — CN claimed
EP-3060669-B1 AAV-5 PSEUDOTYPED VECTOR FOR GENE THERAPY FOR NEUROLOGICAL DISEASES UNIQURE IP BV (NL) 2024-12-11 — — EP claimed
WO-2023229403-A1 YDJC INHIBITOR SCREENING METHOD 동국대학교 산학협력단 2023-11-30 — — WO claimed
EP-3782639-B1 COMPOSITIONS AND METHODS FOR INTERNALIZING ENZYMES REGENERON PHARMA (US) 2022-07-20 — — EP claimed
EP-3256594-B1 ENHANCED DELIVERY OF VIRAL PARTICLES TO THE STRIATUM AND CORTEX GENZYME CORP (US) 2021-10-20 — — EP claimed
US-12636307-B2 In vitro heparin and heparan sulfate compositions and methods of making and using TEGA THERAPEUTICS, INC. (US) 2026-05-26 — — US disclosed
US-20260042998-A1 Glyco-Engineered Yeast for Therapeutic Protein Production VIB VZW (BE) 2026-02-12 — — US disclosed
EP-4578462-A2 DERMAL FILLER COMPOSITIONS ALLERGAN Industrie, SAS (FR) 2025-07-02 — — EP disclosed
EP-4570825-A2 THE IN VIVO USE OF CHONDROITINASE AND/OR HYALURONIDASE TO ENHANCE DELIVERY OF AN AGENT Inovio Pharmaceuticals, Inc. (US) 2025-06-18 — — EP disclosed
US-20250179211-A1 Antibodies and antibody fragments and analogues specific for chondroitin sulfate VAR2 PHARMACEUTICALS APS (DK) 2025-06-05 — — US disclosed
US-20250154476-A1 IMPROVED HEPARAN SULFATE AND METHODS OF MAKING THE SAME UNIVERSITY OF COPENHAGEN (DK) 2025-05-15 — — US disclosed
EP-3448993-B1 THE IN VIVO USE OF CHONDROITINASE AND/OR HYALURONIDASE TO ENHANCE DELIVERY OF AN AGENT INOVIO PHARMACEUTICALS INC (US) 2025-04-30 — — EP disclosed
CN-110542728-B Reagents and methods for screening MPS I, II, IIIA, IIIB, IVA, VI and VII 华盛顿大学商业中心 2022-05-24 — — CN disclosed
US-20220142948-A1 COMPOSITIONS AND METHODS FOR MODULATING METABOLIC REGULATORS OF T CELL PATHOGENICITY MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2022-05-12 — — US disclosed
EP-3969014-A1 METHOD FOR MODULATING ENDOTHELIAL GLYCOCALYX STRUCTURE ExThera Medical Corporation (US) 2022-03-23 — — EP disclosed
US-20220023186-A1 DERMAL FILLER COMPOSITIONS ALLERGAN INDUSTRIE, SAS (FR) 2022-01-27 — — US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 — — US disclosed
US-10286045-B2 Subcutaneous therapeutic enzyme formulations, uses, and methods for generating thereof KINETIQ, INC. (US) 2019-05-14 — — US disclosed
US-20180236048-A1 SUBCUTANEOUS THERAPEUTIC ENZYME FORMULATIONS, USES, AND METHODS FOR GENERATING THEREOF KINETIQ THERAPEUTICS, LLC 2018-08-23 — — US disclosed
CN-105899154-A Injection device for minimally invasive surgical procedures and applications thereof 全球生物疗法有限公司 2016-08-24 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220023186-A1 DERMAL FILLER COMPOSITIONS CD44, HACD3, CUTA MAPK1 4233/4885AMDHD2 58/4885ALDH1A1 822/4885
US-12636307-B2 In vitro heparin and heparan sulfate compositions and methods of making and using TPST2, CSGALNACT1, B4GALT1 MAPK1 2095/4885AMDHD2 268/4885ALDH1A1 2044/4885
US-20260042998-A1 Glyco-Engineered Yeast for Therapeutic Protein Production MAN2A1, OGA, ERG28 MAPK1 612/4885AMDHD2 324/4885ALDH1A1 3093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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