Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MPL | P40238 | 2/20 | 0.38 |
| ▸ | TOP1 | P11387 | 3/20 | 0.38 |
| ▸ | CYCS | P99999 | 2/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2317190 | 0.89 | TOP1 (0.42) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL2364029 | 0.86 | TOP1 (0.55) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL29910098 | 0.82 | STAT3 (0.39) | ALDH1A1MAPT | |
| SCHEMBL6014909 | 0.81 | STAT3 (0.36) | MPLTOP1 | |
| SCHEMBL4944703 | 0.81 | STAT3 (0.40) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3720959 | 0.79 | STAT3 (0.37) | ALDH1A1MAPT | |
| SCHEMBL6003904 | 0.79 | STAT3 (0.41) | ALDH1A1MAPT | |
| SCHEMBL3522373 | 0.79 | STAT3 (0.41) | ALDH1A1MAPT | |
| SCHEMBL15510967 | 0.79 | STAT3 (0.41) | ALDH1A1MAPT | |
| SCHEMBL3520094 | 0.79 | STAT3 (0.41) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350058-A2 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | CeramOptec GmbH (DE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010033678-A2 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | CERAMOPTEC INDUSTRIES, INC. (US) | 2010-03-25 | — | — | WO | disclosed |