Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.75 |
| ▸ | CYCS | P99999 | 4/20 | 0.73 |
| ▸ | STAT3 | P40763 | 1/20 | 0.62 |
| ▸ | STAT1 | P42224 | 1/20 | 0.62 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22332272 | 0.97 | TOP1 (0.70) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL140681 | 0.95 | TOP1 (0.67) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL17894094 | 0.95 | TOP1 (0.75) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL11334086 | 0.94 | TOP1 (0.65) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL28919688 | 0.94 | TOP1 (0.65) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL22332236 | 0.89 | TOP1 (0.60) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL28071729 | 0.89 | TOP1 (0.63) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL26285347 | 0.88 | TOP1 (0.57) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL14246834 | 0.87 | CYCS (0.62) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL29664855 | 0.87 | CYCS (0.62) | TOP1CYCSSTAT3STAT1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256597-A | DETERGENT AND PHOTOINITIATOR COMPRISING A PORPHINE OR MONO, DI, OR TRIAZO PORPHINE, OR PHTHALOCYANINE COMPOUND; WATER SOLUBILITY; STAIN REMOVAL | THE PROCTER & GAMBLE COMPANY (US) | 1981-03-17 | — | — | US | disclosed |